Recombinant Mouse Mstn protein(Asp268-Ser376), hFc-tagged
Cat.No. : | Mstn-490M |
Product Overview : | Recombinant Mouse MSTN (NP_034964.1) (Asp 268-Ser 376) was expressed in HEK293, fused with the Fc region of Human IgG1 at the N-terminus. |
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Source : | HEK293 |
Species : | Mouse |
Tag : | N-hFc |
Protein length : | Asp268-Ser376 |
Form : | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. |
Molecular Mass : | The recombinant mouse MSTN/Fc is a disulfide-linked homodimeric protein. The reduced monomer consists of 369 amino acids and has a predicted molecular mass of 40.8 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rmMSTN/Fc monomer is approximately 45 kDa. |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method. |
Purity : | > 92 % as determined by SDS-PAGE |
Storage : | Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | Mstn myostatin [ Mus musculus ] |
Official Symbol : | Mstn |
Synonyms : | MSTN; myostatin; growth/differentiation factor 8; GDF-8; compact; growth differentiation factor 8; Cmpt; Gdf8; MGC124261; MGC124262; MGC124263; |
Gene ID : | 17700 |
mRNA Refseq : | NM_010834 |
Protein Refseq : | NP_034964 |
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◆ Lysates | ||
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionMSTN inhibitors work by blocking the activity of the MSTN protein, thus promoting muscle growth and potentially reversing muscle loss.
Some potential side effects include joint stiffness, increased risk of fractures, and insulin resistance, which require close monitoring during trials.
Overexpression of MSTN can lead to muscle atrophy and decreased muscle mass.
Researchers carefully monitor the dosage and administration of MSTN protein therapy through preclinical and clinical studies to establish the optimal therapeutic dose.
Possible risks include unintended effects on other organ systems and potential complications related to excessive muscle growth.
Customer Reviews (3)
Write a reviewThe MSTN protein surpasses expectations in terms of quality and will undoubtedly fulfill my experimental requirements.
the manufacturer of MSTN provides exceptional technical support, offering valuable assistance in troubleshooting and experimental design.
The outstanding level of customer service adds extra reassurance and confidence in using the MSTN protein for my scientific investigations.
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