Recombinant Human RAC3

• Cat.No.: RAC3-3391H
• Product Overview: Recombinant human RAC3 protein was expressed inE.coliand purified by using conventional chromatography techniques. MW = 21kDa (189aa).

Specification

• Cat. No.: RAC3-3391H
• Description: RAC3 is a member of the Rac subfamily of the Rho small G proteins.This protein is a small (~21 kDa) monomeric GTP-binding protein, and is an important component of intracellular signalling pathway, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases.
• Source: E.coli.
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 2mM DTT, 200mM NaCl, 0.1mM PMSF, 1mM EDTA.
• Purity: > 95% by SDS - PAGE.
• Concentration: 1 mg/ml (determined by Bradford assay).
• Sequences Of Amino Acids: MQAIKCVVVG DGAVGKTCLL ISYTTNAFPG EYIPTVFDNY SANVMVDGKP VNLGLWDTAG QEDYDRLRPL SYPQTDVFLI CFSLVSPASF ENVRAKWYPE VRHHCPHTPI LLVGTKLDLR DDKDTIERLR DKKLAPITYP QGLAMAREIG SVKYLECSAL TQRGLKTVFD EAIRAVLCPP PVKKPGKKC.
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Pathways: Adherens junction; Axon guidance; B cell receptor signaling pathway; Colorectal cancer; Fc epsilon RI signaling pathway; Focal adhesion; MAPK signaling pathway; Natural killer cell mediated cytotoxicity; Pancreatic cancer; Pathways in cancer; Regulation of actin cytoskeleton; VEGF signaling pathway; Wnt signaling pathway

Gene Information

• Gene Name: RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) [ Homo sapiens ]
• Synonyms: RAC3; ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3); rho family, small GTP binding protein Rac3; Ras-related C3 botulinum toxin substrate 3; p21-Rac3
• Gene ID: 5881
• mRNA Refseq: NM_005052
• Protein Refseq: NP_005043
• MIM: 602050
• UniProt ID: P60763
• Chromosome Location: 17q25.3
• Function: GTP binding; GTPase activity; nucleotide binding; protein binding