Recombinant Human RALA, His-tagged

• Cat.No.: RALA-3386H
• Product Overview: Recombinant human RALA protein, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography techniques.MW = 25.8kDa (227aa).

Specification

• Cat. No.: RALA-3386H
• Description: RALA (Ras-related protein Ral-A) belongs to the small GTPase superfamily, Ras family of proteins. RALA mediates a distinct downstream signaling pathway from Ras that facilitates cellular transformation. RALA is also thought to be involved in numerous signaling cascades, including regulation of the cytoskeleton, vesicle trafficking, and endocytosis.
• Source: E.coli.
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol,2mM DTT, 100mM NaCl, 0.1mM PMSF.
• Purity: > 90% by SDS - PAGE.
• Concentration: 0.5 mg/ml (determined by Bradford assay).
• Sequences Of Amino Acids: MGSSHHHHHH SSGLVPRGSH MGSHMAANKP KGQNSLALHK VIMVGSGGVG KSALTLQFMY DEFVEDYEPT KADSYRKKVV LDGEEVQIDI LDTAGQEDYA AIRDNYFRSG EGFLCVFSIT EMESFAATAD FREQILRVKE DENVPFLLVG NKSDLEDKRQ VSVEEAKNRA EQWNVNYVET SAKTRANVDK VFFDLMREIR ARKMEDSKEK NGKKKRKSLA KRIRERC.
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Pathways: Pancreatic cancer; Pathways in cancer; Signalling by NGF

Gene Information

• Gene Name: RALA v-ral simian leukemia viral oncogene homolog A (ras related) [ Homo sapiens ]
• Synonyms: v-ral simian leukemia viral oncogene homolog A (ras related); RAL; MGC48949; RALA;ras-related protein Ral-A; OTTHUMP00000207663; RAS-like protein A; Ras family small GTP binding protein RALA
• Gene ID: 5895
• mRNA Refseq: NM_005402
• Protein Refseq: NP_005393
• MIM: 179550
• UniProt ID: P11233
• Chromosome Location: 7p15-p13
• Function: Edg-2 lysophosphatidic acid receptor binding; GTP binding; nucleotide binding; GTPase activity; protein binding