Recombinant Human CEACAM8 protein, His-tagged
Cat.No. : | CEACAM8-3233H |
Product Overview : | Recombinant Human CEACAM8 (Gln35-Ser319) protein was fused to His-tag at C-terminus and expressed in human 293 cells (HEK293). |
Unit | |
Price | |
Qty |
- Specification
- Gene Information
- Related Products
Description : | Carcinoembryonic antigen-related cell adhesion molecule 8 (CEACAM8) is also known as CD66b (Cluster of Differentiation 66b), CD66b, CD67, CGM6, NCA-95, and is one of seven human CEACAM family members within the immunoglobulin superfamily. CEACAM family members are a set of widely expressed proteins involved in several biological functions, including cell adhesion, migration, signal transduction, and the regulation of gene expression. Abnormal overexpression and downregulation of some CEACAMs have been described in tumor cells. In humans, CEACAMs include type I transmembrane proteins (CEACAM1, CEACAM3, and CEACAM4) and GPI-linked molecules (CEACAM5 through CEACAM8). There is no human CEACAM2. CEACAM8 is a single chain, two Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. It is an activation marker for human granulocytes. |
Source : | HEK293 |
Species : | Human |
Tag : | His |
Predicted N Terminal : | Gln35 |
Form : | Lyophilized from 0.22 μm filtered solution in PBS, pH7.4, 10% trehalose. |
Molecular Mass : | The protein has a calculated MW of 33.0 kDa. The protein migrates as 53-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Protein length : | Gln35-Ser319 |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20 to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | CEACAM8 |
Official Symbol : | CEACAM8 |
Synonyms : | CEACAM8; carcinoembryonic antigen-related cell adhesion molecule 8; CGM6; CD66b; CD67 antigen; carcinoembryonic antigen CGM6; non-specific cross-reacting antigen NCA-95; carcinoembryonic antigen gene family member 6; CD67; NCA-95 |
Gene ID : | 1088 |
mRNA Refseq : | NM_001816 |
Protein Refseq : | NP_001807 |
MIM : | 615747 |
UniProt ID : | P31997 |
Products Types
◆ Recombinant Protein | ||
CEACAM8-734H | Recombinant Human CEACAM8 Protein, His-tagged | +Inquiry |
CEACAM8-04H | Recombinant human CEACAM8 protein, His-tagged | +Inquiry |
CEACAM8-1162H | Recombinant Human CEACAM8 Protein, His-SUMO-tagged | +Inquiry |
CEACAM8-180H | Recombinant Human CEACAM8 Protein, His-tagged | +Inquiry |
CEACAM8-1098H | Recombinant Human CEACAM8 Protein, GST-Tagged | +Inquiry |
◆ Lysates | ||
CEACAM8-2246HCL | Recombinant Human CEACAM8 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (7)
Ask a questionGenetic variations in CEACAM8 affect immune function and infection susceptibility.
It aids neutrophil adhesion, migration, and antibacterial functions.
CEACAM8 plays a role in regulating inflammation and immune responses.
CEACAM8 works with other adhesion molecules, impacting immune cell signaling.
Altered CEACAM8 expression is linked to autoimmune diseases and chronic inflammation.
Targeting CEACAM8 offers potential treatments for immune-related conditions.
CEACAM8 is key in immune cell activation and signaling, especially in neutrophils.
Customer Reviews (3)
Write a reviewTrusted partner. Contributes to our research discoveries.
Essential for research milestones. Highly recommended service.
Efficient and accurate. A research game-changer.
Ask a Question for All CEACAM8 Products
Required fields are marked with *
My Review for All CEACAM8 Products
Required fields are marked with *
Inquiry Basket