Recombinant Human NEK7, His & GST tagged
Cat.No. : | NEK7-761H |
Product Overview : | Recombinant Human NEK7 (NP_003461.2) (Met1-Ser 302), fused with the N-terminal polyhistidine-tagged GST tag, was produced in Baculovirus-Insect cells. |
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Source : | Baculovirus-Insect Cells |
Species : | Human |
Tag : | His & GST |
Form : | Lyophilized from sterile 50mM Tris, 100mM NaCl, pH 8.5, 0.5mM Reduced Glutathione, 0.5mM PMSF |
Molecular Mass : | The recombinant human NEK7/GST chimera consists of 539 amino acids and has a calculated molecular mass of 62.4 kDa. It migrates as an approximately 58 kDa band in SDS-PAGE under reducing conditions. |
Endotoxin : | < 1.0 eu per μg of the protein as determined by the LAL method. |
Stability : | Samples are stable for up to twelve months from date of receipt at -70oC. |
Storage : | Store it under sterile conditions at -20oC~-70oC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | NEK7 NIMA (never in mitosis gene a)-related kinase 7 [ Homo sapiens ] |
Official Symbol : | NEK7 |
Gene ID : | 140609 |
mRNA Refseq : | NM_133494 |
Protein Refseq : | NP_598001 |
MIM : | 606848 |
UniProt ID : | Q8TDX7 |
Products Types
◆ Recombinant Protein | ||
NEK7-3611H | Recombinant Human NEK7 Protein, His (Fc)-Avi-tagged | +Inquiry |
NEK7-2818R | Recombinant Rhesus Macaque NEK7 Protein, His (Fc)-Avi-tagged | +Inquiry |
NEK7-588H | Recombinant Human NEK7 Protein, MYC/DDK-tagged | +Inquiry |
Nek7-4369M | Recombinant Mouse Nek7 Protein, Myc/DDK-tagged | +Inquiry |
NEK7-6011M | Recombinant Mouse NEK7 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
NEK7-654HCL | Recombinant Human NEK7 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionNEK7 is crucial for mitotic progression, contributing to spindle assembly and chromosome segregation. It phosphorylates key proteins involved in these processes, ensuring accurate distribution of genetic material during cell division.
NEK7 has been implicated in neurological disorders, with evidence linking its dysregulation to disease pathology. NEK7 activity is involved in cellular processes critical for nervous system function.
NEK7 dysregulation is observed in various cancers, suggesting its involvement in tumorigenesis. The identification of NEK7-associated therapeutic targets holds promise for cancer treatment strategies.
NEK7 expression is tightly regulated during the cell cycle. Dysregulation of NEK7 is associated with disruptions in cellular homeostasis and has implications in diseases such as cancer and neurodegeneration.
NEK7 plays a role in the innate immune response by interacting with the NLRP3 inflammasome, contributing to its activation. Dysregulation of this process is implicated in inflammatory diseases, and NEK7 is a potential therapeutic target.
Customer Reviews (3)
Write a reviewGreat service, exceptional product quality
Our lab swears by this protein. Fast shipping is a definite bonus.
Superb quality, accompanied by excellent service.
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