Recombinant Mouse Prlr protein, His&hFc-tagged
Cat.No. : | Prlr-213M |
Product Overview : | Recombinant Mouse Prlr protein(NP_035299.4)(Met1-Asp229), fused with His and hFc tag, was expressed in HEK293. |
Unit | |
Price | |
Qty |
- Specification
- Gene Information
- Related Products
Source : | HEK293 |
Species : | Mouse |
Tag : | His&hFc |
Form : | Lyophilized from sterile PBS, pH 7.4Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. |
Molecular Mass : | The recombinant mouse PRLR/Fc chimera is a disulfide-linked homodimer. The reduced monomer consists of 457 amino acids and has a calculated molecular mass of 52.5 kDa. As a result of glycosylation, the apparent molecular mass of the mouse PRLR/Fc monomer is approximately 65-70 kDa in SDS-PAGE under reducing conditions. |
Protein Length : | Met1-Asp229 |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method |
Purity : | > 90 % as determined by SDS-PAGE |
Storage : | Samples are stable for up to twelve months from date of receipt at -20°C to -80°C Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | Prlr prolactin receptor [ Mus musculus ] |
Official Symbol : | Prlr |
Synonyms : | PRLR; prolactin receptor; PRL-R; prolactin receptor related sequence 1; Pr-1; Pr-3; AI987712; Prlr-rs1; |
Gene ID : | 19116 |
mRNA Refseq : | NM_001253781 |
Protein Refseq : | NP_001240710 |
Products Types
◆ Recombinant Protein | ||
PRLR-719B | Recombinant Bovine PRLR Protein, His-tagged | +Inquiry |
PRLR-1247M | Recombinant Mouse PRLR protein(Met1-Asp229), His-tagged | +Inquiry |
PRLR-135H | Recombinant Human PRLR Protein, His (Fc)-Avi-tagged | +Inquiry |
Prlr-7003R | Recombinant Rat Prlr protein(Met1-Asp229), His-tagged | +Inquiry |
Prlr-721R | Recombinant Rat Prlr Protein, His-tagged | +Inquiry |
◆ Lysates | ||
PRLR-2722HCL | Recombinant Human PRLR cell lysate | +Inquiry |
PRLR-1451MCL | Recombinant Mouse PRLR cell lysate | +Inquiry |
PRLR-1740RCL | Recombinant Rat PRLR cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (5)
Ask a questionPRLR overexpression or dysregulation has been associated with breast cancer. It can promote cell proliferation and survival through aberrant signaling pathways.
Tissue-specific factors and the presence of co-receptors contribute to the diversity of PRLR signaling outcomes in different tissues and cell types.
The JAK-STAT signaling pathway is a primary pathway activated by PRLR. It involves the activation of Janus kinases (JAKs) and signal transducers and activators of transcription (STATs).
PRLR undergoes endocytosis upon ligand binding, and the internalized receptor-ligand complex is trafficked through intracellular compartments, influencing downstream signaling and receptor recycling.
Phosphorylation is a crucial post-translational modification of PRLR, affecting its activation and downstream signaling. Other modifications, such as glycosylation, also play roles.
Customer Reviews (3)
Write a reviewConsistent quality shines through—this protein has become indispensable.
This protein streamlines our experiments.
Fast shipping made this purchase convenient for our lab operations.
Ask a Question for All Prlr Products
Required fields are marked with *
My Review for All Prlr Products
Required fields are marked with *
Inquiry Basket