Recombinant Human Quinolinate Phosphoribosyltransferase, His-tagged
Cat.No. : | QPRT-2814H |
Product Overview : | Recombinant human QPRT protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. MW =32.9 kDa (317aa), confirmed by MALDI-TOF. |
- Specification
- Gene Information
- Related Products
Cat. No. : | QPRT-2814H |
Description : | Quinolinate phosphoribosyltransferase, also known as QPRT, is a major enzyme in the catabolism of quinolinate. It is an intermediate in the tryptophannicotinamide adenine dinucleotide (NAD) pathway, leading to the production of nicotinic acid, carbon dioxide and pyrophosphate. Elevation of QPRT levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer"s disease, and Huntington"s disease. |
Source : | E.coli. |
Sequences Of Amino Acids : | MGSSHHHHHH SSGLVPRGSH MDAEGLALLL PPVTLAALVD SWLREDCPGL NYAALVSGAG PSQAALWAKS PGVLAGQPFF DAIFTQLNCQ VSWFLPEGSK LVPVARVAEV RGPAHCLLLG ERVALNTLAR CSGIASAAAA AVEAARGAGW TGHVAGTRKT TPGFRLVEKY GLLVGGAASH RYDLGGLVMV KDNHVVAAGG VEKAVRAARQ AADFALKVEV ECSSLQEAVQ AAEAGADLVL LDNFKPEELH PTATVLKAQF PSVAVEASGG ITLDNLPQFC GPHIDVISMG MLTQAAPALD FSLKLFAKEV APVPKIH |
Purity : | > 95% by SDS – PAGE. |
Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol. |
Concentration : | 1mg/ml (determined by Bradford assay). |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Gene Name : | QPRT quinolinate phosphoribosyltransferase [ Homo sapiens ] |
Synonyms : | QPRT; quinolinate phosphoribosyltransferase; QPRTase; nicotinate-nucleotide pyrophosphorylase [carboxylating]; QAPRTase; nicotinate-nucleotide pyrophosphorylase (carboxylating); EC 2.4.2.19; nicotinate-nucleotide pyrophosphorylase |
Gene ID : | 23475 |
mRNA Refseq : | NM_014298 |
Protein Refseq : | NP_055113 |
MIM : | 606248 |
UniProt ID : | Q15274 |
Chromosome Location : | 16p11.2 |
Pathway : | Metabolic pathways; Nicotinate and nicotinamide metabolism |
Function : | nicotinate-nucleotide diphosphorylase (carboxylating) activity; nicotinate-nucleotide diphosphorylase (carboxylating) activity; protein homodimerization activity; transferase activity, transferring glycosyl groups |
Products Types
◆ Recombinant Protein | ||
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QPRT-7324M | Recombinant Mouse QPRT Protein, His (Fc)-Avi-tagged | +Inquiry |
QPRT-30232TH | Recombinant Human QPRT, His-tagged | +Inquiry |
QPRT-30231TH | Recombinant Human QPRT, T7 -tagged | +Inquiry |
◆ Lysates | ||
QPRT-2637HCL | Recombinant Human QPRT 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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