Cat. No. : | IGF2-457H |
Product Overview : | Recombinant Human Insulin-like Growth Factor 2 (Somatomedin A) is expressed inyeast. |
Description : | Human IGF-II is a potent mitogen for cells of mesodermal origin. It is composed of 67 amino acid residues, and is 62% homologous with human IGF-I. |
Source : | Human IGF-II is produced by genetically engineeredyeast, and purified by sequential chromatography. |
Molecular Weight : | 7.5 kDa. |
Biological Activity : | The material is active in a receptor-binding assay using a membrane preparation from placenta. |
Purity : | Over 95% pure by N-terminal amino acid sequencing, amino acid composition, HPLC analysis, and SDS gel electrophoresis. |
Storage And Reconstitution : | Store at +4°C. Reconstitution is best in water or buffer near neutral pH. After reconstitution, storage in aliquots at -80 °C is recommended. |
Gene Name : | IGF2 insulin-like growth factor 2 (somatomedin A) [ Homo sapiens ] |
Synonyms : | insulin-like growth factor 2 (somatomedin A);INSIGF; pp9974; C11orf43; FLJ22066; FLJ44734; IGF2; insulin-like growth factor 2; IGF-II; somatomedin A; somatomedin-A; insulin-like growth factor II; insulin-like growth factor type 2; putative insulin-like growth factor II associated protein; chromosome 11 open reading frame 43; OTTHUMP00000011157; OTTHUMP00000011018 |
Gene ID : | 3481 |
mRNA Refseq : | NM_000612 |
Protein Refseq : | NP_000603 |
MIM : | 147470 |
UniProt ID : | P01344 |
Chromosome Location : | 11p15.5 |
Pathway : | Diabetes pathways |
Function : | growth factor activity; hormone activity; insulin receptor binding; insulin-like growth factor receptor binding; protein binding |
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