Recombinant Human Mitogen-activated Protein Kinase 8, His-tagged MAPK8-612H

Recombinant Human Mitogen-activated Protein Kinase 8, His-tagged

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Recombinant Human Mitogen-activated Protein Kinase 8, His-tagged

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Cat. No. : MAPK8-612H
Product Overview : Recombinant Human full length JNK1ß2 (MAPK8) produced ininsect cellsis fused to an N-terminal His-tag, 48 kDa.
Description : JNK1 is the major c-Jun kinase after stimulation by inflammatory cytokines and environmental stresses. JNK phosphorylates nuclear receptors c-Jun, ATF-2, p53, Elk- and NFAT1.
Source : insect cells.
Long Term Storage : -80°C.
PDB rendering based on 1jnk. :

Gene Name : MAPK8 mitogen-activated protein kinase 8 [ Homo sapiens ]
Synonyms : mitogen-activated protein kinase 8; JNK; JNK1; PRKM8; SAPK1; JNK1A2; JNK21B1/2; MAPK8; JNK-46; MAPK 8; MAP kinase 8; protein kinase JNK1; JUN N-terminal kinase; JNK1 beta protein kinase; JNK1 alpha protein kinase; c-Jun N-terminal kinase 1; stress-activated protein kinase 1; stress-activated protein kinase JNK1; mitogen-activated protein kinase 8 isoform JNK1 beta2; mitogen-activated protein kinase 8 isoform JNK1 alpha1; Stress-activated protein kinase JNK1; OTTHUMP00000019552; EC 2.7.11.24
Gene ID : 5599
mRNA Refseq : NM_002750
Protein Refseq : NP_002741
MIM : 601158
UniProt ID : P45983
Chromosome Location : 10q11.22
Pathway : Adipocytokine signaling pathway; Colorectal cancer; Epithelial cell signaling in Helicobacter pylori infection; ErbB signaling pathway; Fc epsilon RI signaling pathway; Focal adhesion; GnRH signaling pathway; Insulin signaling pathway; MAPK signaling pathway; NOD-like receptor signaling pathway; Neurotrophin signaling pathway; Pancreatic cancer; Pathways in cancer; Progesterone-mediated oocyte maturation; RIG-I-like receptor signaling pathway; Toll-like receptor signaling pathway; Type II diabetes mellitus; Wnt signaling pathway
Function : ATP binding; JUN kinase activity; MAP kinase activity; kinase activity; nucleotide binding; protein binding; protein serine/threonine kinase activity; transferase activity

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