Nucleosomes (Chicken Mono/Di)


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Cat.No.:  NUC-0006
Product Name:  Nucleosomes (Chicken Mono/Di)
Description:  Mono/di-nucleosomes purified from chicken blood cells. These are core nucleosomes comprising histone octamers (two copies each of histones H3, H4, H2A, H2B), each wrapped with ~146 bp of DNA with ~50 additional bp of internucleosomal DNA. Useful for the assay of various histone methyltransferases (e.g. MLL1 Complex, MLL2 Complex, MLL4 Complex, Dot1L and NSD2) by methods employing radiolabeling with [3H]-S-adenosylmethionine (e.g. gel electrophoresis/autoradiography or filterplate/scintillation counting). Most histone methyltransferases that require nucleosomes for assay have roughly equal or somewhat greater activity with chicken, relative to HeLa, nucleosomes.
Storage:  Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles.
Source:  Chicken blood cells
Species:  Chicken
Warning:  This product is for research use only. Not for use in diagnostic or therapeutic procedures.

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