Recombinant Human MBD3 Cell Lysate


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Cat.No.:  EL-0002
Product Name:  Recombinant Human MBD3 Cell Lysate
Description:  DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). However, unlike the other family members, MBD3 is not capable of binding to methylated DNA. The predicted MBD3 protein shares 71% and 94% identity with MBD2 (isoform 1) and mouse Mbd3. MBD3 is a subunit of the NuRD, a multisubunit complex containing nucleosome remodeling and histone deacetylase activities. MBD3 mediates the association of metastasis-associated protein 2 (MTA2) with the core histone deacetylase complex.
Species:  Human
Warning:  For research use only, not for diagnostic or therapeutic use.
Gene ID NCBI:  8931
Official Symbol:  MBD3
Official Full Name:  methyl-CpG binding domain protein 3
Synonyms:  MBD3; methyl-CpG binding domain protein 3;

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