| Cat.No.: | PE-0256 |
| Product Name: | Recombinant Human DNMT1, GST-tagged |
| Product Overview: | Recombinant Human DNMT1, (a-a 2-1632), with N-terminal GST tag expressed in baculovirus . MW= 211 kDa. |
| Description: | DNA (cytosine-5-)-methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Aberrant methylation patterns are associated with certain human tumors and developmental abnormalities. |
| Applications: | Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Purity: | >50%. |
| Species: | Human |
| Formulation: | 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20 and 10% glycerol. |
| Tag: | GST |
| Expression System: | Baculovirus |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | DNMT1 DNA (cytosine-5-)-methyltransferase 1 [ Homo sapiens ] |
| Gene ID NCBI: | 1786 |
| Synonyms: | DNMT1; DNA (cytosine-5-)-methyltransferase 1; AIM; DNMT; MCMT; CXXC9; FLJ16293; MGC104992; CXXC finger protein 9; DNA methyltransferase 1; EC 2.1.1.37; Dnmt1; DNA methyltransferase HsaI; DNA MTase HsaI; M.HsaI; CXXC-type zinc finger protein 9 |
| mRNA Refseq: | NM_001130823 |
| Protein Refseq: | NP_001124295 |
| MIM: | 126375 |
| UniProt ID: | P26358 |
| Chromosome Location: | 19p13.2 |
| Function: | DNA (cytosine-5-)-methyltransferase activity; DNA binding; metal ion binding; transcription factor binding; transferase activity; zinc ion binding |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0008 | Vinorelbine Tartrate | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0027 | Recombinant Human DNMT3A 293 Cell Lysate | Inquiry |
| EL-0028 | Recombinant Human DNMT3B 293 Cell Lysate | Inquiry |
| EL-0029 | Recombinant Human DNMT3L 293 Cell Lysate | Inquiry |
| EL-0030 | Recombinant Human DNMT3L 293 Cell Lysate | Inquiry |
| Related Gene / Proteins | |||
| DNA alkyltransferase | DNAJC2 | DNAS1L1 | DNASE1L3 |
| DNMT | DNMT1 | DNMT2 | DNMT3A |
| DNMT3B | DNMT3L | DNMT4 | |
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