| Cat.No.: | PE-0408 |
| Product Name: | Recombinant Human MECP2 protein, His-tagged |
| Product Overview: | Recombinant human MECP2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
| Description: | MECP2, also known as methyl-CpG-binding protein 2 isoform 1, is found in all cells in the body, including the brain, acting as a transcriptional repressor and activator. In the brain, it is found in high concentrations in neurons and is associated with maturation of the central nervous system (CNS) and in forming synaptic contacts. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | 53.2kDa (492aa)50-70kDa (SDS-PAGE under reducing conditions) |
| Purity: | >90% by SDS – PAGE |
| Species: | Human |
| Formulation: | Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol. |
| Tag: | His |
| Amino Acid Sequence: | MVAGMLGLRE EKSEDQDLQG LKDKPLKFKK VKKDKKEEKE GKHEPVQPSA HHSAEPAEAG KAETSEGSGS APAVPEASAS PKQRRSIIRDRGPMYDDPTL PEGWTRKLKQ RKSGRSAGKY DVYLINPQGK AFRSKVELIA YFEKVGDTSL DPNDFDFTVT GRGSPSRREQ KPPKKPKSPKAPGTGRGRGR PKGSGTTRPK AATSEGVQVK RVLEKSPGKL LVKMPFQTSP GGKAEGGGAT TSTQVMVIKR PGRKRKAEAD PQAIPKKRGRKPGSVVAAAA AEAKKKAVKE SSIRSVQETV LPIKKRKTRE TVSIEVKEVV KPLLVSTLGE KSGKGLKTCK SPGRKSKESS PKGRSSSASSPPKKEHHHHH HHSESPKAPV PLLPPLPPPP PEPESSEDPT SPPEPQDLSS SVCKEEKMPR GGSLESDGCP KEPAKTQPAV ATAATAAEKYKHRGEGERKD IVSSSMPRPN REEPVDSRTP VTERVSHHHH HH |
| Endotoxin: | < 1.0 EU per 1 microgram of protein (determined by LAL method) |
| Expression System: | Insect Cells |
| Concentrations: | 0.5mg/ml (determined by Bradford assay) |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | MECP2 methyl CpG binding protein 2 (Rett syndrome) [ Homo sapiens ] |
| Gene ID NCBI: | 4204 |
| Official Symbol: | MECP2 |
| Synonyms: | MECP2; methyl CpG binding protein 2 (Rett syndrome); mental retardation, X linked 16 , mental retardation, X linked 79 , MRX16, MRX79, RTT; methyl-CpG-binding protein 2; meCp-2 protein; RS; RTS; RTT; PPMX; MRX16; MRX79; MRXSL; AUTSX3; MRXS13; DKFZp686A24160; |
| mRNA Refseq: | NM_001110792 |
| Protein Refseq: | NP_001104262 |
| MIM: | 300005 |
| UniProt ID: | P51608 |
| Chromosome Location: | Xq28 |
| Function: | DNA binding; double-stranded methylated DNA binding; protein N-terminus binding; protein binding; protein domain specific binding; transcription corepressor activity; |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0043 | Recombinant Human MECP2 293 Cell Lysate | Inquiry |
| EL-0111 | Recombinant Human MEF2B Cell Lysate | Inquiry |
| ◆ Antibodies | ||
| EAb-0067 | MeCP2 Polyclonal Antibody | Inquiry |
| ◆ Cell Lines | ||
| CL-0109 | Human MECP2 Knockout Cell Line 1bp insertion | Inquiry |
| CL-0110 | Human MEN1 Knockout Cell Line 1bp insertion | Inquiry |
USA
Enter your email here to subscribe.
Follow us on
Easy access to products and services you need from our library via powerful searching tools
