Recombinant Human H2AFZ, His-tagged


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  • Gene Information
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Cat.No.:  PE-0553
Product Name:  Recombinant Human H2AFZ, His-tagged
Product Overview:  Recombinant human H2AFZ protein, fused to His-tag at N-terminus, was expressed in E.coli.
Description:  Histone H2A.Z, also known as H2AFZ, is a member of the histone H2A family. Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). H2AFZ may be involved in the formation of constitutive heterochromatin and may be required for chromosome segregation during cell division. Also, H2AFZ is a variant Histone H2A which replaces conventional H2A in a subset of nucleosomes.
Applications:  SDS-PAGE
Storage:  Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles.
Molecular Weight:  15.9 kDa (151aa)
Purity:  >85% by SDS - PAGE
Species:  Human
Formulation:  Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 10% glycerol
Tag:  His
Amino Acid Sequence:  MGSSHHHHHH SSGLVPRGSH MGSMAGGKAG KDSGKAKTKA VSRSQRAGLQ FPVGRIHRHL KSRTTSHGRV GATAAVYSAA ILEYLTAEVL ELAGNASKDL KVKRITPRHL QLAIRGDEEL DSLIKATIAG GGVIPHIHKS LIGKKGQQKT V
Expression System:  E. coli
Concentrations:  0.25 mg/ml (determined by Bradford assay)
Warning:  This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Gene Name:  H2AFZ H2A histone family, member Z [ Homo sapiens ]
Gene ID NCBI:  3015
Synonyms:  H2AFZ; H2A histone family, member Z; H2AZ; histone H2A.Z; H2A.Z; H2AZ histone; H2A.z; H2A/z; MGC117173;
mRNA Refseq:  NM_002106
Protein Refseq:  NP_002097
MIM:  142763
UniProt ID:  P0C0S5
Chromosome Location:  4q23
Function:  DNA binding;

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