| Cat.No.: | PE-1188 |
| Product Name: | Recombinant Human TET3, GST-tagged |
| Product Overview: | Recombinant human TET3 (724-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
| Description: | TET3 or Tet methylcytosine deoxygenase 3 is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. TET3 which is a member of the ten-eleven translocation (TET) gene family is involved in myelopoiesis, and defects in TET3 have been associated with several myeloproliferative disorders. TET plays an important role in embryonic stem cell maintenance and inner cell mass cell specification. TET3 play an important role in the DNA methylation process. |
| Applications: | Western Blot |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | ~140 kDa |
| Purity: | >70% by densitometry |
| Species: | Human |
| Formulation: | Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
| Tag: | GST |
| Expression System: | Sf9 Insect Cells |
| Concentrations: | 0.1 μg/μl |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | TET3?tet methylcytosine dioxygenase 3 [?Homo sapiens?(human) ] |
| Gene ID NCBI: | 200424 |
| Synonyms: | TET3; hCG_40738; tet methylcytosine dioxygenase 3; methylcytosine dioxygenase TET3; tet oncogene family member 3; probable methylcytosine dioxygenase TET3; EC 1.14.11.n2 |
| mRNA Refseq: | NM_144993 |
| Protein Refseq: | NP_659430 |
| MIM: | 613555 |
| UniProt ID: | O43151 |
| Chromosome Location: | 2p13.1 |
| Function: | metal ion binding; methylcytosine dioxygenase activity; protein binding |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0154 | Recombinant Human TET3 Cell Lysate | Inquiry |
| ◆ Antibodies | ||
| EAb-0176 | TEAD2 Polyclonal Antibody | Inquiry |
| ◆ Cell Lines | ||
| CL-0215 | Human TET1 Knockout Cell Line 1bp insertion | Inquiry |
| CL-0217 | Human TET2 Knockout Cell Line 19bp deletion | Inquiry |
| CL-0218 | Human TET3 Knockout Cell Line 14bp deletion | Inquiry |
| Related Gene / Proteins | |||
| TEAD1 | TEAD2 | telomerase | TEN1 |
| TENR | TERF2IP | TET | TET1 |
| TET2 | TET3 | ||
USA
Enter your email here to subscribe.
Follow us on
Easy access to products and services you need from our library via powerful searching tools
