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Active GMP Recombinant Human BMP4 protein, Fc-tagged

Cat.No. : BMP4-1325HG
Product Overview : GMP Recombinant Human BMP4 protein(NP_001334841.1)(354 aa), fused with Fc Tag at the C-terminal, was expressed in HEK293 cell in an animal component free process under cGMP guidelines.
  • Specification
  • Gene Information
  • Related Products
Source : HEK293
Species : Human
Tag : Fc
Bio-activity : This depends on its ability to induce ATDC-5 cells to produce alkaline phosphatase, and the expected ED50 effectiveness is 4-16ng/ml.
Molecular Mass : Recombinant Human BMP-4 contains 354 aa. It has a predicted MW of 40.1 kDa.
Protein length : DNA sequence encoding Human BMP-4(NP_001334841.1 ) was expressed with Fc tag at the C-terminal.
Endotoxin : <=0.01EU/ug
Purity : >=95% by SDS-PAGE and HPLC
Storage : The lyophilized preparation can be stored at 4°C for 24 months, and the dissolved liquid can be stored at -20°C for 6-12 months to avoid repeated freezing and thawing
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Gene Name : BMP4 bone morphogenetic protein 4 [ Homo sapiens ]
Official Symbol : BMP4
Synonyms : BMP4; bone morphogenetic protein 4; BMP2B; BMP-4; BMP-2B; bone morphogenetic protein 2B; ZYME; OFC11; BMP2B1; MCOPS6;
Gene ID : 652
mRNA Refseq : NM_001202
Protein Refseq : NP_001193
MIM : 112262
UniProt ID : P12644

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How is BMP4 applied in spinal fusion surgery? 03/30/2022

BMP4 can be used in spinal fusion surgery to stimulate bone growth and fuse vertebrae together, which can alleviate back pain and stabilize the spine.

Are there any genetic disorders related to BMP4? 07/03/2020

Mutations in BMP4 or its receptors can lead to congenital disorders, such as orofacial clefts and heart defects.

Are there ongoing clinical trials involving BMP4 in regenerative medicine? 07/12/2019

Yes, there are ongoing trials exploring the use of BMP4 in regenerative medicine for conditions like osteoarthritis and tendon injuries.

Are there any potential risks or side effects associated with the clinical use of BMP4? 06/11/2018

Yes, some risks include excessive bone growth, swelling, and inflammation at the application site. These complications can be carefully managed by healthcare providers.

Can BMP4 be used in cosmetic surgery? 02/10/2017

Yes, BMP4 can be used to aid in tissue regeneration in cosmetic procedures, such as in the reconstruction of facial bone defects or enhancement of soft tissue volume.

Customer Reviews (3)

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Reviews
11/22/2020

    The BMP4 protein is a valuable resource for researchers due to its high quality and its ability to meet specific experimental needs.

    08/26/2020

      the manufacturer's technical support team can offer prompt assistance in case any issues arise during the handling or application of the BMP4 protein.

      06/05/2018

        The manufacturer's support can play a crucial role in assisting researchers throughout their trials.

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