Active Native Human alpha-Thrombin
Cat.No. : | Thrombin-23H |
Product Overview : | Native Human alpha-Thrombin was purified from Plasma. |
- Specification
- Gene Information
- Related Products
Description : | Alpha-thrombin is a highly specific serine protease generated by proteolytic activation of the zymogen prothrombin. During coagulation, thrombin cleaves fibrinogen to form fibrin, leading to the ultimate step in coagulation, the formation of a fibrin clot. Thrombin is also responsible for feedback activation of the procofactors factor V and factor VIII. Thrombin has also been reported to activate factor XIII and platelets, and also functions as a vasoconstrictor protein. The procoagulant activity of thrombin is arrested in two ways: 1) inhibition by either heparin cofactor II or the antithrombin III/heparin complex; or 2) complex formation with thrombomodulin. Formation of the thrombin/thrombomodulin complex results in the inability of thrombin to cleave fibrinogen and activate factors V and VIII, but increases the efficiency of thrombin for activation of the anticoagulant, protein C. |
Source : | Plasma |
Species : | Human |
Form : | 50% glycerol/water (v/v) |
Bio-activity : | 4493 U/mg |
Molecular Mass : | 36700 Da |
Purity : | >95% by SDS-PAGE |
Storage : | Glyercol formulation: -20°CHepes formulation: -80°C |
Concentration : | 8.9 mg/mL |
Products Types
◆ Native Protein | ||
Thrombin-24H | Active Native Human a-Thrombin | +Inquiry |
Thrombin-29B | Active Native Bovine alpha-Thrombin-FPRck | +Inquiry |
Thrombin-25H | Active Native Human β-thrombin | +Inquiry |
◆ Assay kits | ||
Kit-0338 | Thrombin Activity Fluorometric Assay Kit | +Inquiry |
Kit-0982 | Thrombin Generation Assay Kit | +Inquiry |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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