Native Porcine GPT protein


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Native Porcine GPT protein

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Cat.No. : GPT-189P
Product Overview : Native Porcine GPT was purified from Porcine Heart.
Description : This gene encodes cytosolic alanine aminotransaminase 1 (ALT1); also known as glutamate-pyruvate transaminase 1. This enzyme catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate and, therefore, plays a key role in the intermediary metabolism of glucose and amino acids. Serum activity levels of this enzyme are routinely used as a biomarker of liver injury caused by drug toxicity, infection, alcohol, and steatosis. A related gene on chromosome 16 encodes a putative mitochondrial alanine aminotransaminase.
Source : Porcine Heart
Species : Porcine
Form : Lyophilized from tris-HCl, sodium chloride, EDTA, DTE, a-ketoglutarate and phridoxal-5-phosphate
Bio-activity : > 80 U/mg protein
Molecular Mass : ~100 kDa
Unit Definition : One unit will catalyze the transamination of one micromole per minute of L-alanine to a-ketoglutarate, forming L-glutamate and pyruvate, at 37 centigrade and pH 7.4.
Storage : Store at -20 centigrade
Concentration : > 0.8 mg protein/mg solid (A280)
Reconstitution : Clear, yellow-green in 10 mg/mL saline.
Gene Name : GPT glutamic-pyruvate transaminase (alanine aminotransferase) [ Sus scrofa ]
Official Symbol : GPT
Synonyms : glutamic-pyruvate transaminase (alanine aminotransferase)
Gene ID : 100524618
mRNA Refseq :
Protein Refseq :
UniProt ID :
Chromosome Location : chromosome: 4
Pathway : 2-Oxocarboxylic acid metabolism, organism-specific biosystem; Alanine, aspartate and glutamate metabolism, organism-specific biosystem; Arginine biosynthesis, organism-specific biosystem

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