Active Recombinant Cotton Rat Il6, Met-tagged
Cat.No. : | Il6-392C |
Product Overview : | Recombinant Cotton Rat Il6 (Accession # AAL18819) Leu25-Asn212, fused with an N-terminal Met, was produced in E. coli-derived. |
- Specification
- Gene Information
- Related Products
Source : | E. coli |
Species : | Cotton Rat |
Predicted N Terminal : | Met |
Form : | Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA with BSA as a carrier protein. |
Bio-activity : | Measured in a cell proliferation assay using T1165.85.2.1 mouse plasmacytoma cells. Nordan, R.P. et al. (1987) J. Immunol. 139:813.The ED50 for this effect is typically 0.02-0.06 ng/mL. |
Molecular Mass : | Recombinant Cotton Rat Il6, Met-tagged has a calculated MW of 22 kDa. |
Purity : | >97%, by SDS-PAGE under reducing conditions and visualized by silver stain. |
Storage : | Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC). |
Reconstitution : | Reconstitute at 100 µg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin. |
Gene Name : | Il6 interleukin 6 [ Rattus norvegicus (Norway rat) ] |
Official Symbol : | Il6 |
Synonyms : | Il6; interleukin 6; ILg6; Ifnb2; interleukin-6; IL-6; Interleukin 6 (interferon, beta 2) |
Gene ID : | 24498 |
mRNA Refseq : | NM_012589 |
Protein Refseq : | NP_036721 |
MIM : | |
UniProt ID : | P20607 |
Chromosome Location : | 4q11 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionThe dosage and usage of Il6 will vary according to the disease, and generally require individualized regulation by the physician according to the disease situation.
The pharmacokinetic characteristics of Il6 mainly include drug absorption, distribution, metabolism, excretion and other information.
Recombinant Il6 protein has a unique therapeutic advantage in the treatment of multiple myeloma. It can promote the proliferation and differentiation of hematopoietic stem cells and inhibit the growth of tumor cells.
Il6 has specific therapeutic effects for certain diseases, such as rheumatoid arthritis, multiple myeloma and so on.
This protein is widely used in the treatment of rheumatoid arthritis, pneumonia, multiple myeloma, lymphoma, malignant tumors and other diseases.
The effects of Il6 on immune cells are mainly manifested as promoting cell proliferation and differentiation, regulating immune response, etc.
Customer Reviews (3)
Write a reviewAccurate localization and function within the cell.
The binding affinity and affinity constant with the target are high.
Can form a stable micellar structure.
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