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Recombinant Full Length Mouse Cadherin-1(Cdh1) Protein, His-Tagged

Cat.No. : RFL732MF
Product Overview : Recombinant Full Length Mouse Cadherin-1(Cdh1) Protein (P09803) (157-884aa), fused to N-terminal His tag, was expressed in E. coli.
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  • Gene Information
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Source : E.coli expression system
Species : Mus musculus (Mouse)
Tag : His
Form : Lyophilized powder
Protein length : Full Length of Mature Protein (157-884)
AA Sequence : DWVIPPISCPENEKGEFPKNLVQIK SNRDKETKVFYSITGQGADKPPVGV FIIERETGWLKVTQPLDREAIAKYI LYSHAVSSNGEAVEDPMEIVITVTD QNDNRPEFTQEVFEGSVAEGAVPGT SVMKVSATDADDDVNTYNAAIAYTI VSQDPELPHKNMFTVNRDTGVISVL TSGLDRESYPTYTLVVQAADLQGEG LSTTAKAVITVKDINDNAPVFNPST YQGQVPENEVNARIATLKVTDDDAP NTPAWKAVYTVVNDPDQQFVVVTDP TTNDGILKTAKGLDFEAKQQYILHV RVENEEPFEGSLVPSTATVTVDVVD VNEAPIFMPAERRVEVPEDFGVGQE ITSYTAREPDTFMDQKITYRIWRDT ANWLEINPETGAIFTRAEMDREDAE HVKNSTYVALIIATDDGSPIATGTG TLLLVLLDVNDNAPIPEPRNMQFCQ RNPQPHIITILDPDLPPNTSPFTAE LTHGASVNWTIEYNDAAQESLILQP RKDLEIGEYKIHLKLADNQNKDQVT TLDVHVCDCEGTVNNCMKAGIVAAG LQVPAILGILGGILALLILILLLLL FLRRRTVVKEPLLPPDDDTRDNVYY YDEEGGGEEDQDFDLSQLHRGLDAR PEVTRNDVAPTLMSVPQYRPRPANP DEIGNFIDENLKAADSDPTAPPYDS LLVFDYEGSGSEAASLSSLNSSESD QDQDYDYLNEWGNRFKKLADMYGGG EDD
Purity : Greater than 90% as determined by SDS-PAGE.
Applications : SDS-PAGE
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Storage : Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Storage Buffer : Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution : We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Gene Name : Cdh1
Synonyms : Cdh1; Cadherin-1; ARC-1; Epithelial cadherin; E-cadherin; Uvomorulin; CD antigen CD324
UniProt ID : P09803
Gene Name : Cdh1
Synonyms : Cdh1; Cadherin-1; ARC-1; Epithelial cadherin; E-cadherin; Uvomorulin; CD antigen CD324
UniProt ID : P09803

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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How about the inheritance pattern of CDH1 gene mutations? 09/25/2019

CDH1 gene mutations are usually passed on in an autosomal dominant manner, depending on the type and location of the mutation.

What screening is required for carriers of CDH1 gene mutations? 08/03/2019

Carriers of CDH1 gene mutations should have gastroscopy, ultrasonography, and other related tests to monitor the development and progression of stomach cancer.

Can CDH1 gene mutations be prevented or treated? 06/14/2019

For people with mutations in the CDH1 gene, prophylactic total gastrectomy may reduce the risk of diffuse stomach cancer. There is currently no specific treatment to target CDH1 gene mutations.

Which gastric cancer subtypes are associated with CDH1 mutations? 04/21/2019

CDH1 gene mutation is closely related to the occurrence of diffuse gastric cancer, which is a special subtype of gastric cancer with a high degree of invasion and malignancy.

What are the effects of CDH1 gene mutations on cell adhesion and tissue differentiation? 04/01/2019

The CDH1 gene encodes a protein called E-calcin that plays an important role in cell adhesion and tissue differentiation. Mutations in the CDH1 gene may affect these processes, resulting in abnormal cell adhesion and tissue differentiation.

What is the relationship between CDH1 gene mutations and breast cancer? 03/24/2019

CDH1 gene mutations may be associated with the development of a small number of breast cancers, because CDH1 also plays a role in regulating cell adhesion and tissue structure in breast tissue.

Customer Reviews (3)

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Reviews
04/22/2022

    This recombinant protein has a very short half-life and shows a very high clearance rate, which makes its biological activity more stable.

    05/27/2020

      The protein was highly purified and was not doped with other proteins or impurities.

      05/21/2019

        CDH1 has similar activity to the native protein and is able to perform the expected biological functions.

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