Recombinant Human A2ML1 Protein, GST-tagged A2ML1-004H

Recombinant Human A2ML1 Protein, GST-tagged

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Recombinant Human A2ML1 Protein, GST-tagged

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Cat.No. : A2ML1-004H
Product Overview : Human A2ML1 full-length ORF ( AAH93840.1, 1 a.a. - 158 a.a.) recombinant protein with GST-tag at N-terminal.
Description : This gene encodes a member of the alpha-macroglobulin superfamily. The encoded protein is thought to be an N-glycosylated monomeric protein that acts as an inhibitor of several proteases. It has been shown to form covalent interactions with proteases, and has been reported as the p170 antigen recognized by autoantibodies in the autoimmune disease paraneoplastic pemphigus (PNP; PMID:20805888). Mutations in these gene have also been associated with some cases of Noonan syndrome (NS; PMID:24939586) as well as some cases of otitis media (PMID:26121085). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 44.1 kDa
AA Sequence : MYTLEASGQGCVYVQ TVLRYNILPPTNMKT FSLSVEIGKARCEQP TSPRSLTLTIHTSYV GSRSSSNMAIVEVKM LSGFSPMEGTNQLLL QQPLVKKVEFGTDTL NIYLDELIKNTQTYT FTISQSVLVTNLKPA TIKVYDYYLPDEQAT IQYSDPCE
Applications : Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : A2ML1 alpha-2-macroglobulin-like 1 [ Homo sapiens ]
Official Symbol : A2ML1
Synonyms : A2ML1; alpha-2-macroglobulin-like 1; C3 and PZP like, alpha 2 macroglobulin domain containing 9 , CPAMD9; alpha-2-macroglobulin-like protein 1; FLJ25179; C3 and PZP-like, alpha-2-macroglobulin domain containing 9; CPAMD9; FLJ16045; FLJ39129; FLJ41597; FLJ41598; FLJ41607; DKFZp686C1729; DKFZp686D2011; DKFZp686G1812; DKFZp686L1821; DKFZp686O1010;
Gene ID : 144568
mRNA Refseq : NM_144670
Protein Refseq : NP_653271
MIM : 610627
UniProt ID : A8K2U0

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