| Description : |
This gene encodes a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. This gene is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members; however, its specific function remains unknown. This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes. [provided by RefSeq, Jul 2008] |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
MYC/DDK |
| Form : |
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol. |
| Molecular Mass : |
43.3 kDa |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration : |
>50 ug/mL as determined by microplate BCA method |
