| Description : |
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. Expression of this gene may be regulated by the cytokine TNF-alpha. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
122.7 kDa |
| AA Sequence : |
MEILWKTLTWILSLIMASSEFHSDH RLSYSSQEEFLTYLEHYQLTIPIRV DQNGAFLSFTVKNDKHSRRRRSMDP IDPQQAVSKLFFKLSAYGKHFHLNL TLNTDFVSKHFTVEYWGKDGPQWKH DFLDNCHYTGYLQDQRSTTKVALSN CVGLHGVIATEDEEYFIEPLKNTTE DSKHFSYENGHPHVIYKKSALQQRH LYDHSHCGVSDFTRSGKPWWLNDTS TVSYSLPINNTHIHHRQKRSVSIER FVETLVVADKMMVGYHGRKDIEHYI LSVMNIVAKLYRDSSLGNVVNIIVA RLIVLTEDQPNLEINHHADKSLDSF CKWQKSILSHQSDGNTIPENGIAHH DNAVLITRYDICTYKNKPCGTLGLA SVAGMCEPERSCSINEDIGLGSAFT IAHEIGHNFGMNHDGIGNSCGTKGH EAAKLMAAHITANTNPFSWSACSRD YITSFLDSGRGTCLDNEPPKRDFLY PAVAPGQVYDADEQCRFQYGATSRQ CKYGEVCRELWCLSKSNRCVTNSIP AAEGTLCQTGNIEKGWCYQGDCVPF GTWPQSIDGGWGPWSLWGECSRTCG GGVSSSLRHCDSPAPSGGGKYCLGE RKRYRSCNTDPCPLGSRDFREKQCA DFDNMPFRGKYYNWKPYTGGGVKPC ALNCLAEGYNFYTERAPAVIDGTQC NADSLDICINGECKHVGCDNILGSD AREDRCRVCGGDGSTCDAIEGFFND SLPRGGYMEVVQIPRGSVHIEVREV AMSKNYIALKSEGDDYYINGAWTID WPRKFDVAGTAFHYKRPTDEPESLE ALGPTSENLIVMVLLQEQNLGIRYK FNVPITRTGSGDNEVGFTWNHQPWS ECSATCAGGVQRQEVVCKRLDDNSI VQNNYCDPDSKPPENQRACNTEPCP PEWFIGDWLECSKTCDGGMRTRAVL CIRKIGPSEEETLDYSGCLTHRPVE KEPCNNQSCPPQWVALDWSECTPKC GPGFKHRIVLCKSSDLSKTFPAAQC PEESKPPVRIRCSLGRCPPPRWVTG DWGQCSAQCGLGQQMRTVQCLSYTG QASSDCLETVRPPSMQQCESKCDST PISNTEECKDVNKVAYCPLVLKFKF CSRAYFRQMCCKTCQGHTRTRPLEQ KLISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
