| Description : |
This gene is a member of the FAD-binding oxidoreductase/transferase type 4 family. It encodes a protein that catalyzes the second step of ether lipid biosynthesis in which acyl-dihydroxyacetonephosphate (DHAP) is converted to alkyl-DHAP by the addition of a long chain alcohol and the removal of a long-chain acid anion. The protein is localized to the inner aspect of the peroxisomal membrane and requires FAD as a cofactor. Mutations in this gene have been associated with rhizomelic chondrodysplasia punctata, type 3 and Zellweger syndrome. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
72.91 kDa |
| AA Sequence : |
MAEAAAAAGGTGLGAGASYGSAADR DRDPDPDRAGRRLRVLSGHLLGRPR EALSTNECKARRAASAATAAPTATP AAQESGTIPKKRQEVMKWNGWGYND SKFIFNKKGQIELTGKRYPLSGMGL PTFKEWIQNTLGVNVEHKTTSKASL NPSDTPPSVVNEDFLHDLKETNISY SQEADDRVFRAHGHCLHEIFLLREG MFERIPDIVLWPTCHDDVVKIVNLA CKYNLCIIPIGGGTSVSYGLMCPAD ETRTIISLDTSQMNRILWVDENNLT AHVEAGITGQELERQLKESGYCTGH EPDSLEFSTVGGWVSTRASGMKKNI YGNIEDLVVHIKMVTPRGIIEKSCQ GPRMSTGPDIHHFIMGSEGTLGVIT EATIKIRPVPEYQKYGSVAFPNFEQ GVACLREIAKQRCAPASIRLMDNKQ FQFGHALKPQVSSIFTSFLDGLKKF YITKFKGFDPNQLSVATLLFEGDRE KVLQHEKQVYDIAAKFGGLAAGEDN GQRGYLLTYVIAYIRDLALEYYVLG ESFETSAPWDRVVDLCRNVKERITR ECKEKGVQFAPFSTCRVTQTYDAGA CIYFYFAFNYRGISDPLTVFEQTEA AAREEILANGGSLSHHHGVGKLRKQ WLKESISDVGFGMLKSVKEYVDPNN IFGNRNLLTRTRPLEQKLISEEDLA ANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
