Recombinant Human AK2 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: AK2-685H
• Product Overview: AK2 MS Standard C13 and N15-labeled recombinant protein (NP_001616) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Three isozymes of adenylate kinase, namely 1, 2, and 3, have been identified in vertebrates; this gene encodes isozyme 2. Expression of these isozymes is tissue-specific and developmentally regulated. Isozyme 2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis. Mutations in this gene are the cause of reticular dysgenesis. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 1 and 2.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 26.5 kDa
• AA Sequence: MAPSVPAAEPEYPKGIRAVLLGPPG AGKGTQAPRLAENFCVCHLATGDML RAMVASGSELGKKLKATMDAGKLVS DEMVVELIEKNLETPLCKNGFLLDG FPRTVRQAEMLDDLMEKRKEKLDSV IEFSIPDSLLIRRITGRLIHPKSGR SYHEEFNPPKEPMKDDITGEPLIRR SDDNEKALKIRLQAYHTQTTPLIEY YRKRGIHSAIDASQTPDVVFASILA AFSKATCKDLVMFITRTRPLEQKLI SEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: AK2 adenylate kinase 2 [ Homo sapiens (human) ]
• Official Symbol: AK2
• Synonyms: AK2; adenylate kinase 2; adenylate kinase 2, mitochondrial; ATP-AMP transphosphorylase 2; adenylate kinase isoenzyme 2, mitochondrial; ADK2; AK 2
• Gene ID: 204
• mRNA Refseq: NM_001625
• Protein Refseq: NP_001616
• MIM: 103020
• UniProt ID: P54819