Recombinant Human ALG2 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: ALG2-6198H
• Product Overview: ALG2 MS Standard C13 and N15-labeled recombinant protein (NP_149078) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of the glycosyltransferase 1 family. The encoded protein acts as an alpha 1,3 mannosyltransferase, mannosylating Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. Defects in this gene have been associated with congenital disorder of glycosylation type Ih (CDG-Ii). Alternative splicing results in multiple transcript variants.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 47.1 kDa
• AA Sequence: MAEEQGRERDSVPKPSVLFLHPDLG VGGAERLVLDAALALQARGCSVKIW TAHYDPGHCFAESRELPVRCAGDWL PRGLGWGGRGAAVCAYVRMVFLALY VLFLADEEFDVVVCDQVSACIPVFR LARRRKKILFYCHFPDLLLTKRDSF LKRLYRAPIDWIEEYTTGMADCILV NSQFTAAVFKETFKSLSHIDPDVLY PSLNVTSFDSVVPEKLDDLVPKGKK FLLLSINRYERKKNLTLALEALVQL RGRLTSQDWERVHLIVAGGYDERVL ENVEHYQELKKMVQQSDLGQYVTFL RSFSDKQKISLLHSCTCVLYTPSNE HFGIVPLEAMYMQCPVIAVNSGGPL ESIDHSVTGFLCEPDPVHFSEAIEK FIREPSLKATMGLAGRARVKEKFSP EAFTEQLYRYVTKLLVTRTRPLEQK LISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: ALG2 ALG2 alpha-1,3/1,6-mannosyltransferase [ Homo sapiens (human) ]
• Official Symbol: ALG2
• Synonyms: ALG2; asparagine-linked glycosylation 2, alpha-1,3-mannosyltransferase homolog (S. cerevisiae); asparagine linked glycosylation 2 homolog (yeast, alpha 1,3 mannosyltransferase); alpha-1,3/1,6-mannosyltransferase ALG2; CDGIi; FLJ14511; hALPG2; NET38; homolog of yeast ALG2; alpha-1,3-mannosyltransferase ALG2; asparagine-linked glycosylation protein 2 homolog; GDP-Man:Man(1)GlcNAc(2)-PP-dolichol mannosyltransferase; GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase; GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase; asparagine-linked glycosylation 2 homolog (yeast, alpha-1,3-mannosyltransferase); asparagine-linked glycosylation 2 homolog (S. cerevisiae, alpha-1,3-mannosyltransferase)
• Gene ID: 85365
• mRNA Refseq: NM_033087
• Protein Refseq: NP_149078
• MIM: 607905
• UniProt ID: Q9H553