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Recombinant Human AP1B1 protein, His&Myc-tagged

Cat.No. : AP1B1-4359H
Product Overview : Recombinant Human AP1B1 protein(Q10567)(1-584aa), fused to N-terminal His tag and C-terminal Myc tag, was expressed in E. coli
  • Specification
  • Gene Information
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Source : E. coli
Species : Human
Tag : His&Myc
Form : If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Molecular Mass : 73.3 kDa
Protein length : 1-584aa
AA Sequence : MTDSKYFTTTKKGEIFELKAELNSD KKEKKKEAVKKVIASMTVGKDVSAL FPDVVNCMQTDNLELKKLVYLYLMN YAKSQPDMAIMAVNTFVKDCEDPNP LIRALAVRTMGCIRVDKITEYLCEP LRKCLKDEDPYVRKTAAVCVAKLHD INAQLVEDQGFLDTLKDLISDSNPM VVANAVAALSEIAESHPSSNLLDLN PQSINKLLTALNECTEWGQIFILDC LANYMPKDDREAQSICERVTPRLSH ANSAVVLSAVKVLMKFMEMLSKDLD YYGTLLKKLAPPLVTLLSAEPELQY VALRNINLIVQKRPEILKHEMKVFF VKYNDPIYVKLEKLDIMIRLASQAN IAQVLAELKEYATEVDVDFVRKAVR AIGRCAIKVEQSAERCVSTLLDLIQ TKVNYVVQEAIVVIKDIFRKYPNKY ESVIATLCENLDSLDEPEARAAMIW IVGEYAERIDNADELLESFLEGFHD ESTQVQLQLLTAIVKLFLKKPTETQ ELVQQVLSLATQDSDNPDLRDRGYI YWRLLSTDPVAAKEVVLAEKPLISE ETDLIEPTLLDELICYIGTLASVYH KPPSAFVEG
Purity : Greater than 85% as determined by SDS-PAGE.
Storage : Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Reconstitution : Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%.
Gene Name : AP1B1 adaptor-related protein complex 1, beta 1 subunit [ Homo sapiens ]
Official Symbol : AP1B1
Synonyms : AP1B1; adaptor-related protein complex 1, beta 1 subunit; ADTB1, CLAPB2; AP-1 complex subunit beta-1; AP105A; BAM22; beta1-adaptin; beta-1-adaptin; beta-adaptin 1; beta-prime-adaptin; Golgi adaptor HA1/AP1 adaptin beta subunit; adaptor protein complex AP-1 subunit beta-1; adapter-related protein complex 1 subunit beta-1; clathrin assembly protein complex 1 beta large chain; plasma membrane adaptor HA2/AP2 adaptor beta subunit; ADTB1; CLAPB2;
Gene ID : 162
mRNA Refseq : NM_001127
Protein Refseq : NP_001118
MIM : 600157
UniProt ID : Q10567

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (14)

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Does AP1B1 mutation cause vision problems? 08/27/2022

AP1B1 mutations may be associated with retinal diseases, but there are relatively few studies directly related to vision problems.

Is AP1B1 mutation associated with mental illness? 06/28/2022

Some studies have shown that the AP1B1 gene mutation may be associated with some mental diseases such as schizophrenia.

What is the effect of AP1B1 mutation on treatment? 04/27/2022

AP1B1 mutation may affect intracellular vesicle transport and membrane protein localization, thus affecting the efficacy of therapy and the action of drugs.

Is AP1B1 mutation related to intelligence development? 04/08/2022

Some studies have shown that mutations in the AP1B1 gene may be associated with diseases related to intellectual development.

What diseases are associated with AP1B1 mutations? 09/07/2021

AP1B1 mutations may be associated with a variety of diseases, including congenital retinitis pigmentosa and neurodegenerative diseases.

Can AP1B1 mutation be repaired by gene editing? 09/07/2021

Gene-editing techniques such as CRISPR-Cas9 could potentially be used to fix AP1B1 mutations, but they are still in the laboratory stage and require further research and trials.

Can AP1B1 mutations be inherited? 05/24/2021

AP1B1 mutation may be hereditary, and the specific inheritance pattern may be related to each specific mutation.

How to treat diseases caused by AP1B1 mutations? 09/17/2020

There is currently no specific treatment for diseases caused by AP1B1 mutations, but the quality of life of patients can be improved through symptom relief treatment and rehabilitation training.

What is the function of AP1B1? 08/22/2020

AP1B1 plays an important role in cell regulation by participating in intracellular vesicle transport and cell membrane protein localization.

How does AP1B1 mutation affect intracellular signaling? 06/09/2020

AP1B1 mutation may lead to the abnormality of intracellular signal transduction pathway and affect the normal process of various biochemical reactions in the cell.

How can AP1B1 mutation be prevented? 06/05/2020

There is currently no direct way to prevent AP1B1 mutations, but a healthy lifestyle and genetic counseling may help reduce the risk of certain genetic diseases.

What is the latest progress of AP1B1 research? 12/03/2019

Recent studies have shown that AP1B1 plays an important role in intracellular vesicle transport and neuronal development.

Does AP1B1 mutation affect life span? 05/16/2019

It is unclear whether AP1B1 mutations directly affect longevity.

How to detect AP1B1 gene mutation? 02/13/2019

AP1B1 gene mutation can be detected by molecular biological methods such as gene sequencing.

Customer Reviews (4)

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Reviews
10/11/2022

    Reproducibility of the AP1B1 is very good, which can reduce the error in the experiment and improve the repeatability of the experiment.

    11/07/2020

      AP1B1 labeling effect is very good, can be used for fluorescence labeling, etc., which is very suitable for our research.

      03/30/2020

        It is very stable, even after multiple uses or storage, its structure and function remain stable, providing strong support for long-term experiments and applications.

        05/21/2019

          Catalytic activity of this protein is very strong, which can make chemical reactions that are difficult to carry out easy to achieve, and has high application potential.

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