| Description : |
Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans-Golgi network to lysosomes. The adaptin family of proteins is composed of four classes of molecules named alpha, beta-, beta prime- and gamma- adaptins. Adaptins, together with medium and small subunits, form a heterotetrameric complex called an adaptor, whose role is to promote the formation of clathrin-coated pits and vesicles. The protein encoded by this gene is a gamma-adaptin protein and it belongs to the adaptor complexes large subunits family. Two transcript variants encoding different isoforms have been found for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
91.5 kDa |
| AA Sequence : |
MPAPIRLRELIRTIRTARTQAEERE MIQKECAAIRSSFREEDNTYRCRNV AKLLYMHMLGYPAHFGQLECFKLIA SQKFTDKRIGYLGAMLLLDERQDVH LLMTNCIKNDLNHSTQFVQGLALCT LGCMGSSEMCRDLAGEVEKLLKTSN SYLRKKAALCAVHVIRKVPELMEMF LPATKNLLNEKNHGVLHTSVVLLTE MCERSPDMLAHFRKNEKLVPQLVRI LKNLIMSGYSPEHDVSGISDPFLQV RILRLLRILGRNDDDSSEAMNDILA QVATNTETSKNVGNAILYETVLTIM DIKSESGLRVLAINILGRFLLNNDK NIRYVALTSLLKTVQTDHNAVQRHR STIVDCLKDLDVSIKRRAMELSFAL VNGNNIRGMMKELLYFLDSCEPEFK ADCASGIFLAAEKYAPSKRWHIDTI MRVLTTAGSYVRDDAVPNLIQLITN SVEMHAYTVQRLYKAILGDYSQQPL VQVAAWCIGEYGDLLVSGQCEEEEP IQVTEDEVLDILESVLISNMSTSVT RGYALTAIMKLSTRFTCTVNRIKKV VSIYGSSIDVELQQRAVEYNALFKK YDHMRSALLERMPVMEKVTTNGPTE IVQTNGETEPAPLETKPPPSGPQPT SQANDLLDLLGGNDITPVIPTAPTS KPSSAGGELLDLLGDINLTGAPAAA PAPASVPQISQPPFLLDGLSSQPLF NDIAAGIPSITAYSKNGLKIEFTFE RSNTNPSVTVITIQASNSTELDMTD FVFQAAVPKTFQLQLLSPSSSIVPA FNTGTITQVIKVLNPQKQQLRMRIK LTYNHKGSAMQDLAEVNNFPPQSWQ TRTRPLEQKLISEEDLAANDILDYK DDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
