Recombinant Human APOA5 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: APOA5-5395H
• Product Overview: APOA5 MS Standard C13 and N15-labeled recombinant protein (NP_443200) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene is an apolipoprotein that plays an important role in regulating the plasma triglyceride levels, a major risk factor for coronary artery disease. It is a component of high density lipoprotein and is highly similar to a rat protein that is upregulated in response to liver injury. Mutations in this gene have been associated with hypertriglyceridemia and hyperlipoproteinemia type 5. This gene is located proximal to the apolipoprotein gene cluster on chromosome 11q23. Alternatively spliced transcript variants encoding the same protein have been identified.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 41.2 kDa
• AA Sequence: MASMAAVLTWALALLSAFSATQARK GFWDYFSQTSGDKGRVEQIHQQKMA REPATLKDSLEQDLNNMNKFLEKLR PLSGSEAPRLPQDPVGMRRQLQEEL EEVKARLQPYMAEAHELVGWNLEGL RQQLKPYTMDLMEQVALRVQELQEQ LRVVGEDTKAQLLGGVDEAWALLQG LQSRVVHHTGRFKELFHPYAESLVS GIGRHVQELHRSVAPHAPASPARLS RCVQVLSRKLTLKAKALHARIQQNL DQLREELSRAFAGTGTEEGAGPDPQ MLSEEVRQRLQAFRQDTYLQIAAFT RAIDQETEEVQQQLAPPPPGHSAFA PEFQQTDSGKVLSKLQARLDDLWED ITHSLHDQGHSHLGDPTRTRPLEQK LISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: APOA5 apolipoprotein A-V [ Homo sapiens (human) ]
• Official Symbol: APOA5
• Synonyms: APOA5; apolipoprotein A-V; APOA V; RAP3; apo-AV; apolipoprotein A5; regeneration-associated protein 3; APOAV; FLJ97995; MGC126836; MGC126838
• Gene ID: 116519
• mRNA Refseq: NM_052968
• Protein Refseq: NP_443200
• MIM: 606368
• UniProt ID: Q6Q788