Active Recombinant Human AREG Protein
Cat.No. : | AREG-002H |
Product Overview : | The mature recombinant human AR protein containing 98aa (S101-K198) without tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). The protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells, and it inhibits the growth of certain aggressive carcinoma cell lines. It also functions in mammary gland, oocyte and bone tissue development. This gene is associated with a psoriasis-like skin phenotype, and is also associated with other pathological disorders, including various types of cancers and inflammatory conditions. |
Source : | E. coli |
Species : | Human |
Bio-activity : | Measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblast cells. The ED50 for this effect is 5-15 ng/mL. |
Molecular Mass : | 11 kDa |
Product-Related Proteins : | 101-198 |
Endotoxin : | < 0.1 EU/μg of the protein as determined by the LAL method |
Purity : | > 95 % as determined by SDS-PAGE |
Storage : | At -80 centigrade. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | PBS |
Gene Name : | AREG amphiregulin [ Homo sapiens (human) ] |
Official Symbol : | AREG |
Synonyms : | AREG; amphiregulin; AR; SDGF; AREGB; CRDGF; amphiregulin; Names; amphiregulin B; colorectum cell-derived growth factor; schwannoma-derived growth factor |
Gene ID : | 374 |
mRNA Refseq : | NM_001657 |
Protein Refseq : | NP_001648 |
MIM : | 104640 |
UniProt ID : | P15514 |
Products Types
◆ Recombinant Protein | ||
AREG-02H | Active Recombinant Human AREG Protein | +Inquiry |
Areg-242M | Recombinant Mouse Areg Protein, His-tagged | +Inquiry |
AREG-195A | Active Recombinant Human AREG Protein | +Inquiry |
AREG-402R | Recombinant Rat AREG Protein, His (Fc)-Avi-tagged | +Inquiry |
Areg-32M | Active Recombinant Mouse Areg protein | +Inquiry |
◆ Lysates | ||
AREG-8762HCL | Recombinant Human AREG 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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