Recombinant Human ARG2 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: ARG2-3403H
• Product Overview: ARG2 MS Standard C13 and N15-labeled recombinant protein (NP_001163) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type II isoform encoded by this gene, is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. The physiologic role of this isoform is poorly understood; it is thought to play a role in nitric oxide and polyamine metabolism. Transcript variants of the type II gene resulting from the use of alternative polyadenylation sites have been described.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 38.6 kDa
• AA Sequence: MSLRGSLSRLLQTRVHSILKKSVHS VAVIGAPFSQGQKRKGVEHGPAAIR EAGLMKRLSSLGCHLKDFGDLSFTP VPKDDLYNNLIVNPRSVGLANQELA EVVSRAVSDGYSCVTLGGDHSLAIG TISGHARHCPDLCVVWVDAHADINT PLTTSSGNLHGQPVSFLLRELQDKV PQLPGFSWIKPCISSASIVYIGLRD VDPPEHFILKNYDIQYFSMRDIDRL GIQKVMERTFDLLIGKRQRPIHLSF DIDAFDPTLAPATGTPVVGGLTYRE GMYIAEEIHNTGLLSALDLVEVNPQ LATSEEEAKTTANLAVDVIASSFGQ TREGGHIVYDQLPTPSSPDESENQA RVRITRTRPLEQKLISEEDLAANDI LDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: ARG2 arginase 2 [ Homo sapiens (human) ]
• Official Symbol: ARG2
• Synonyms: ARG2; arginase, type II; arginase-2, mitochondrial; arginase 2; kidney arginase; type II arginase; nonhepatic arginase; kidney-type arginase; non-hepatic arginase; L-arginine ureahydrolase; L-arginine amidinohydrolase
• Gene ID: 384
• mRNA Refseq: NM_001172
• Protein Refseq: NP_001163
• MIM: 107830
• UniProt ID: P78540