| Description : |
This gene belongs to the RhoGEF subfamily of RhoGTPases. Members of this subfamily are activated by specific guanine nucleotide exchange factors (GEFs) and are involved in signal transduction. The encoded protein shows cytosolic distribution. Alternative splicing results in multiple transcript variants. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
140.2 kDa |
| AA Sequence : |
MASSNPPPQPAIGDQLVPGVPGPSS EAEDDPGEAFEFDDSDDEEDTSAAL GVPSLAPERDTDPPLIHLDSIPVTD PDPAAAPPGTGVPAWVSNGDAADAA FSGARHSSWKRKSSRRIDRFTFPAL EEDVIYDDVPCESPDAHQPGAERNL LYEDAHRAGAPRQAEDLGWSSSEFE SYSEDSGEEAKPEVEVEPAKHRVSF QPKLSPDLTRLKERYARTKRDILAL RVGGRDMQELKHKYDCKMTQLMKAA KSGTKDGLEKTRMAVMRKVSFLHRK DVLGDSEEEDMGLLEVSVSDIKPPA PELGPMPEGLSPQQVVRRHILGSIV QSEGSYVESLKRILQDYRNPLMEME PKALSARKCQVVFFRVKEILHCHSM FQIALSSRVAEWDSTEKIGDLFVAS FSKSMVLDVYSDYVNNFTSAMSIIK KACLTKPAFLEFLKRRQVCSPDRVT LYGLMVKPIQRFPQFILLLQDMLKN TPRGHPDRLSLQLALTELETLAEKL NEQKRLADQVAEIQQLTKSVSDRSS LNKLLTSGQRQLLLCETLTETVYGD RGQLIKSKERRVFLLNDMLVCANIN FKPANHRGQLEISSLVPLGPKYVVK WNTALPQVQVVEVGQDGGTYDKDNV LIQHSGAKKASASGQAQNKVYLGPP RLFQELQDLQKDLAVVEQITLLIST LHGTYQNLNMTVAQDWCLALQRLMR VKEEEIHSANKCRLRLLLPGKPDKS GRPISFMVVFITPNPLSKISWVNRL HLAKIGLREENQPGWLCPDEDKKSK APFWCPILACCIPAFSSRALSLQLG ALVHSPVNCPLLGFSAVSTSLPQGY LWVGGGQEGAGGQVEIFSLNRPSPR TVKSFPLAAPVLCMEYIPELEEEAE SRDESPTVADPSATVHPTICLGLQD GSILLYSSVDTGTQCLVSCRSPGLQ PVLCLRHSPFHLLAGLQDGTLAAYP RTSGGVLWDLESPPVCLTVGPGPVR TLLSLEDAVWASCGPRVTVLEATTL QPQQSFEAHQDEAVSVTHMVKAGSG VWMAFSSGTSIRLFHTETLEHLQEI NIATRTTFLLPGQKHLCVTSLLICQ GLLWVGTDQGVIVLLPVPRLEGIPK ITGKGMVSLNGHCGPVAFLAVATSI LAPDILRSDQEEAEGPRAEEDKPDG QAHEPMPDSHVGRELTRKKGILLQY RLRSTAHLPGPLLSMREPAPADGAA LEHSEEDGSIYEMADDPDIWVRSRP CARDAHRKEICSVAIISGGQGYRNF GSALGSSGRQAPCGETDSTLLIWQV PLMLTRTRPLEQKLISEEDLAANDI LDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
