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Recombinant Human ARL11 Protein, Myc/DDK-tagged, C13 and N15-labeled

Cat.No. : ARL11-963H
Product Overview : ARL11 MS Standard C13 and N15-labeled recombinant protein (NP_612459) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
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  • Gene Information
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Description : This gene encodes a tumor suppressor related to the ADP-ribosylation factor (ARF) family of proteins. The encoded protein may play a role in apoptosis in a caspase-dependent manner. Polymorphisms in this gene have been associated with some familial cancers.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 21.4 kDa
AA Sequence : MGSVNSRGHKAEAQVVMMGLDSAGK TTLLYKLKGHQLVETLPTVGFNVEP LKAPGHVSLTLWDVGGQAPLRASWK DYLEGTDILVYVLDSTDEARLPESA AELTEVLNDPNMAGVPFLVLANKQE APDALPLLKIRNRLSLERFQDHCWE LRGCSALTGEGLPEALQSLWSLLKS RSCMCLQARAHGAERGDSKRSTRTR PLEQKLISEEDLAANDILDYKDDDD KV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Name : ARL11 ADP-ribosylation factor-like 11 [ Homo sapiens (human) ]
Official Symbol : ARL11
Synonyms : ARL11; ADP-ribosylation factor-like 11; ADP-ribosylation factor-like protein 11; ARLTS1; FLJ33930; ADP-ribosylation factor-like tumor suppressor protein 1; MGC17429;
Gene ID : 115761
mRNA Refseq : NM_138450
Protein Refseq : NP_612459
MIM : 609351
UniProt ID : Q969Q4

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (8)

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Does Arl11 have any post-translational modifications? 02/22/2022

Limited information is available regarding post-translational modifications (PTMs) of Arl11. However, like other GTPases, Arl11 may undergo PTMs such as phosphorylation, acetylation, or lipidation. These modifications can potentially regulate its activity, localization, and binding partners.

Is Arl11 evolutionarily conserved across species? 07/29/2021

Arl11 is evolutionarily conserved among various species, including mammals, birds, reptiles, and amphibians. Its conservation suggests a functional importance, although the extent of its conservation and specific roles may differ across different organisms.

Is Arl11 widely expressed in different tissues and cells? 03/15/2021

Limited studies have been conducted on the expression pattern of Arl11. However, available data suggests that Arl11 is expressed in various tissues and cells, although the specific levels and localization may vary.

Does Arl11 play a role in cancer development or progression? 12/15/2019

Currently, there is limited information available regarding the involvement of Arl11 in cancer. However, recent studies have suggested potential associations between altered expression of Arl11 and certain types of cancer, indicating a possible role in tumor biology. Further investigations are needed to determine its precise contribution to cancer development and progression.

Are there any known animal models for studying Arl11? 09/28/2019

To date, there are no known animal models specifically targeting Arl11. Developing animal models, such as knockout or transgenic mice, could provide valuable insights into the physiological functions of Arl11 and its potential implications in human health and disease.

Are there any drugs or inhibitors targeting Arl11? 05/26/2019

As of now, there are no known drugs or specific inhibitors developed to directly target Arl11. The lack of comprehensive studies on Arl11's involvement in diseases has limited the development of therapeutic interventions. Identification of small molecule modulators or inhibitors may require further research.

Are there any known binding partners or interactors of Arl11? 10/28/2017

The binding partners or interactors of Arl11 have not been extensively characterized. Further research is needed to identify potential protein partners that interact with Arl11 and determine their functional significance.

Can Arl11 affect cellular processes beyond vesicle trafficking? 03/18/2017

While vesicle trafficking is the most commonly suggested function of Arl11, its role in other cellular processes cannot be ruled out. Further research may uncover additional functions and pathways influenced by Arl11, contributing to a comprehensive understanding of its biological roles.

Customer Reviews (8)

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Reviews
10/28/2022

    By incorporating Arl11 protein into electron microscopy studies, researchers have gained valuable insights into protein interactions and conformational changes, contributing to a deeper understanding of complex cellular processes.

    04/12/2022

      Their extensive technical expertise and assistance are invaluable in overcoming any challenges that may arise during the experimental process.

      09/15/2020

        Its stability and well-defined structure make it an excellent candidate for visualizing and studying the three-dimensional arrangement of proteins at a high resolution.

        02/17/2020

          Its reliability in ELISA makes it a trusted tool for quantitative and qualitative protein analysis.

          11/02/2018

            the manufacturer's commitment to customer satisfaction extends beyond technical support. They offer a comprehensive range of related products and resources to aid researchers in their trials.

            08/30/2018

              Ankar protein has been successfully utilized in protein electron microscopy structure analysis.

              03/05/2018

                From troubleshooting to optimizing experimental protocols, the manufacturer provides diligent support to ensure the success of the trial.

                08/16/2017

                  This property is particularly beneficial for long-term trials or experiments with extended durations, ensuring consistent performance throughout the entire study period.

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