Recombinant Human ATP1B4 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: ATP1B4-3984H
• Product Overview: ATP1B4 MS Standard C13 and N15-labeled recombinant protein (NP_036201) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene has been found in all vertebrate genomes sequenced to date. However, this gene has undergone a change in function in placental mammals compared to other species. Specifically, in fish, avian, and amphibian species, this gene encodes plasma membrane-bound beta-subunits of Na,K-ATPase. In placental mammals, the encoded protein interacts with the nuclear transcriptional coregulator SKIP and may be involved in the regulation of TGF-beta signaling. Two transcript variants encoding different isoforms have been found for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 40.9 kDa
• AA Sequence: MRRQLRSRRAPSFPYSYRYRLDDPD EANQNYLADEEEEAEEEARVTVVPK SEEEEEEEEKEEEEEEEKEEEEGQG QPTGNAWWQKLQIMSEYLWDPERRM FLARTGLILLIYFFFYASLAAVITL CMYTLFLTISPYIPTFTERVKPPGV MIRPFAHSLNFNFNVSEPDTWQHYV ISLNGFLQGYNDSLQEEMNVDCPPG QYFIQDGNEDEDKKACQFKRSFLKN CSGLEDPTFGYSTGQPCILLKMNRI VGFRPELGDPVKVSCKVQRGDENDI RSISYYPESASFDLRYYPYYGKLTH VNYTSPLVAMHFTDVVKNQAVPVQC QLKGKGVINDVINDRFVGRVIFTLN IETTRTRPLEQKLISEEDLAANDIL DYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: ATP1B4 ATPase Na+/K+ transporting family member beta 4 [ Homo sapiens (human) ]
• Official Symbol: ATP1B4
• Synonyms: ATP1B4; ATPase, Na+/K+ transporting, beta 4 polypeptide; ATPase, (Na+)/K+ transporting, beta 4 polypeptide; protein ATP1B4; X,K-ATPase beta-m subunit; x/potassium-transporting ATPase subunit beta-m
• Gene ID: 23439
• mRNA Refseq: NM_012069
• Protein Refseq: NP_036201
• UniProt ID: Q9UN42