Description : |
The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene. |
Source : |
HEK293 |
Species : |
Human |
Tag : |
Myc/DDK |
Molecular Mass : |
98.2 kDa |
AA Sequence : |
MAWRCPRMGRVPLAWCLALCGWACM APRGTQAEESPFVGNPGNITGARGL TGTLRCQLQVQGEPPEVHWLRDGQI LELADSTQTQVPLGEDEQDDWIVVS QLRITSLQLSDTGQYQCLVFLGHQT FVSQPGYVGLEGLPYFLEEPEDRTV AANTPFNLSCQAQGPPEPVDLLWLQ DAVPLATAPGHGPQRSLHVPGLNKT SSFSCEAHNAKGVTTSRTATITVLP QQPRNLHLVSRQPTELEVAWTPGLS GIYPLTHCTLQAVLSDDGMGIQAGE PDPPEEPLTSQASVPPHQLRLGSLH PHTPYHIRVACTSSQGPSSWTHWLP VETPEGVPLGPPENISATRNGSQAF VHWQEPRAPLQGTLLGYRLAYQGQD TPEVLMDIGLRQEVTLELQGDGSVS NLTVCVAAYTAAGDGPWSLPVPLEA WRPGQAQPVHQLVKEPSTPAFSWPW WYVLLGAVVAAACVLILALFLVHRR KKETRYGEVFEPTVERGELVVRYRV RKSYSRRTTEATLNSLGISEELKEK LRDVMVDRHKVALGKTLGEGEFGAV MEGQLNQDDSILKVAVKTMKIAICT RSELEDFLSEAVCMKEFDHPNVMRL IGVCFQGSERESFPAPVVILPFMKH GDLHSFLLYSRLGDQPVYLPTQMLV KFMADIASGMEYLSTKRFIHRDLAA RNCMLNENMSVCVADFGLSKKIYNG DYYRQGRIAKMPVKWIAIESLADRV YTSKSDVWSFGVTMWEIATRGQTPY PGVENSEIYDYLRRGNRLKQPADCL DGLYALMSRCWELNPQDRPSFTELR EDLENTLKALPPAQEPDEILYVNMD EGGGYPEPPGAAGGADPPTQPDPKD SCSCLTAAEVHPAGRYVLCPSTTPS PAQPADRGSPAAPGQEDGATRTRPL EQKLISEEDLAANDILDYKDDDDKV |
Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : |
50 μg/mL as determined by BCA |
Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |