Recombinant Human BCL2L2 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: BCL2L2-5179H
• Product Overview: BCL2L2 MS Standard C13 and N15-labeled recombinant protein (NP_004041) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream PABPN1 (poly(A) binding protein, nuclear 1) gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 20.8 kDa
• AA Sequence: MATPASAPDTRALVADFVGYKLRQK GYVCGAGPGEGPAADPLHQAMRAAG DEFETRFRRTFSDLAAQLHVTPGSA QQRFTQVSDELFQGGPNWGRLVAFF VFGAALCAESVNKEMEPLVGQVQEW MVAYLETRLADWIHSSGGWAEFTAL YGDGALEEARRLREGNWASVRTVLT GAVALGALVTVGAFFASKTRTRPLE QKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: BCL2L2 BCL2-like 2 [ Homo sapiens (human) ]
• Official Symbol: BCL2L2
• Synonyms: BCL2L2; BCL2-like 2; bcl-2-like protein 2; BCL W; KIAA0271; PPP1R51; protein phosphatase 1; regulatory subunit 51; apoptosis regulator BCL-W; protein phosphatase 1, regulatory subunit 51; BCLW; BCL-W; BCL2-L-2
• Gene ID: 599
• mRNA Refseq: NM_004050
• Protein Refseq: NP_004041
• MIM: 601931
• UniProt ID: Q92843