Recombinant Human BCL3 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: BCL3-1724H
• Product Overview: BCL3 MS Standard C13 and N15-labeled recombinant protein (NP_005169) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 47.4 kDa
• AA Sequence: MDEGPVDLRTRPKAAGLPGAALPLR KRPLRAPSPEPAAPRGAAGLVVPLD PLRGGCDLPAVPGPPHGLARPEALY YPGALLPLYPTRAMGSPFPLVNLPT PLYPMMCPMEHPLSADIAMATRADE DGDTPLHIAVVQGNLPAVHRLVNLF QQGGRELDIYNNLRQTPLHLAVITT LPSVVRLLVTAGASPMALDRHGQTA AHLACEHRSPTCLRALLDSAAPGTL DLEARNYDGLTALHVAVNTECQETV QLLLERGADIDAVDIKSGRSPLIHA VENNSLSMVQLLLQHGANVNAQMYS GSSALHSASGRGLLPLVRTLVRSGA DSSLKNCHNDTPLMVARSRRVIDIL RGKATRPASTSQPDPSPDRSANTSP ESSSRLSSNGLLSASPSSSPSQSPP RDPPGFPMAPPNFFLPSPSPPAFLP FAGVLRGPGRPVPPSPAPGGSTRTR PLEQKLISEEDLAANDILDYKDDDD KV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: BCL3 B-cell CLL/lymphoma 3 [ Homo sapiens (human) ]
• Official Symbol: BCL3
• Synonyms: BCL3; B-cell CLL/lymphoma 3; BCL4, D19S37; B-cell lymphoma 3 protein; B cell leukemia/lymphoma 3; B cell lymphoma 3 encoded protein; chronic lymphatic leukemia protein; BCL-3; proto-oncogene BCL3; B-cell leukemia/lymphoma 3; B-cell lymphoma 3-encoded protein; BCL4; D19S37
• Gene ID: 602
• mRNA Refseq: NM_005178
• Protein Refseq: NP_005169
• MIM: 109560
• UniProt ID: P20749