| Description : |
This gene encodes a lens-specific intermediate filament-like protein named filensin. The encoded protein is expressed in lens fiber cells after differentiation has begun. This protein functions as a component of the beaded filament which is a cytoskeletal structure found in lens fiber cells. Mutations in this gene are the cause of autosomal recessive cortical juvenile-onset cataract. Alternate splicing results in multiple transcript variants. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
74.4 kDa |
| AA Sequence : |
MYRRSYVFQTRKEQYEHADEASRAA EPERPADEGWAGATSLAALQGLGER VAAHVQRARALEQRHAGLRRQLDAF QRLGELAGPEDALARQVESNRQRVR DLEAERARLERQGTEAQRALDEFRS KYENECECQLLLKEMLERLNKEADE ALLHNLRLQLEAQFLQDDISAAKDR HKKNLLEVQTYISILQQIIHTTPPA SIVTSGMREEKLLTEREVAALRSQL EEGREVLSHLQAQRVELQAQTTTLE QAIKSAHECYDDEIQLYNEQIETLR KEIEETERVLEKSSYDCRQLAVAQQ TLKNELDRYHRIIEIEGNRLTSAFI ETPIPLFTQSHGVSLSTGSGGKDLT RALQDITAAKPRQKALPKNVPRRKE IITKDKTNGALEDAPLKGLEDTKLV QVVLKEESESKFESESKEVSPLTQE GAPEDVPDGGQISKGFGKLYRKVKE KVRSPKEPETPTELYTKERHVLVTG DANYVDPRFYVSSITAKGGVAVSVA EDSVLYDGQVEPSPESPKPPLENGQ VGLQEKEDGQPIDQQPIDKEIEPDG AELEGPEEKREGEERDEESRRPCAM VTPGAEEPSIPEPPKPAADQDGAEV LGTRSRSLPEKGPPKALAYKTVEVV ESIEKISTESIQTYEETAVIVETMI GKTKSDKKKSGEKSSTRTRPLEQKL ISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
