Recombinant Human BHMT Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: BHMT-5608H
• Product Overview: BHMT MS Standard C13 and N15-labeled recombinant protein (NP_001704) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a cytosolic enzyme that catalyzes the conversion of betaine and homocysteine to dimethylglycine and methionine, respectively. Defects in this gene could lead to hyperhomocyst(e)inemia, but such a defect has not yet been observed.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 45 kDa
• AA Sequence: MPPVGGKKAKKGILERLNAGEIVIG DGGFVFALEKRGYVKAGPWTPEAAV EHPEAVRQLHREFLRAGSNVMQTFT FYASEDKLENRGNYVLEKISGQEVN EAACDIARQVADEGDALVAGGVSQT PSYLSCKSETEVKKVFLQQLEVFMK KNVDFLIAEYFEHVEEAVWAVETLI ASGKPVAATMCIGPEGDLHGVPPGE CAVRLVKAGASIIGVNCHFDPTISL KTVKLMKEGLEAARLKAHLMSQPLA YHTPDCNKQGFIDLPEFPFGLEPRV ATRWDIQKYAREAYNLGVRYIGGCC GFEPYHIRAIAEELAPERGFLPPAS EKHGSWGSGLDMHTKPWVRARARKE YWENLRIASGRPYNPSMSKPDGWGV TKGTAELMQQKEATTEQQLKELFEK QKFKSQTRTRPLEQKLISEEDLAAN DILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: BHMT betaine--homocysteine S-methyltransferase [ Homo sapiens (human) ]
• Official Symbol: BHMT
• Synonyms: BHMT; betaine--homocysteine S-methyltransferase; betaine--homocysteine S-methyltransferase 1; betaine homocysteine methyltransferase; BHMT1
• Gene ID: 635
• mRNA Refseq: NM_001713
• Protein Refseq: NP_001704
• MIM: 602888
• UniProt ID: Q93088