| Description : |
This gene encodes a protein which is a member of the bromodomain-containing protein family. The product of this gene has been identified as a component of one form of the SWI/SNF chromatin remodeling complex, and as a protein which interacts with p53 and is required for p53-dependent oncogene-induced senescence which prevents tumor growth. Pseudogenes have been described on chromosomes 2, 3, 6, 13 and 14. Alternative splicing results in multiple transcript variants. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
74.1 kDa |
| AA Sequence : |
MGKKHKKHKSDKHLYEEYVEKPLKL VLKVGGNEVTELSTGSSGHDSSLFE DKNDHDKHKDRKRKKRKKGEKQIPG EEKGRKRRRVKEDKKKRDRDRVENE AEKDLQCHAPVRLDLPPEKPLTSSL AKQEEVEQTPLQEALNQLMRQLQRK DPSAFFSFPVTDFIAPGYSMIIKHP MDFSTMKEKIKNNDYQSIEELKDNF KLMCTNAMIYNKPETIYYKAAKKLL HSGMKILSQERIQSLKQSIDFMADL QKTRKQKDGTDTSQSGEDGGCWQRE REDSGDAEAHAFKSPSKENKKKDKD MLEDKFKSNNLEREQEQLDRIVKES GGKLTRRLVNSQCEFERRKPDGTTT LGLLHPVDPIVGEPGYCPVRLGMTT GRLQSGVNTLQGFKEDKRNKVTPVL YLNYGPYSSYAPHYDSTFANISKDD SDLIYSTYGEDSDLPSDFSIHEFLA TCQDYPYVMADSLLDVLTKGGHSRT LQEMEMSLPEDEGHTRTLDTAKEME ITEVEPPGRLDSSTQDRLIALKAVT NFGVPVEVFDSEEAEIFQKKLDETT RLLRELQEAQNERLSTRPPPNMICL LGPSYREMHLAEQVTNNLKELAQQV TPGDIVSTYGVRKAMGISIPSPVME NNFVDLTEDTEEPKKTDVAECGPGG STRTRPLEQKLISEEDLAANDILDY KDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
