| Description : |
This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. Along with a single, unique beta-chain, seven identical alpha-chains encoded by this gene assemble into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Two pseudogenes of this gene are also found in the cluster. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
67 kDa |
| AA Sequence : |
MHPPKTPSGALHRKRKMAAWPFSRL WKVSDPILFQMTLIAALLPAVLGNC GPPPTLSFAAPMDITLTETRFKTGT TLKYTCLPGYVRSHSTQTLTCNSDG EWVYNTFCIYKRCRHPGELRNGQVE IKTDLSFGSQIEFSCSEGFFLIGST TSRCEVQDRGVGWSHPLPQCEIVKC KPPPDIRNGRHSGEENFYAYGFSVT YSCDPRFSLLGHASISCTVENETIG VWRPSPPTCEKITCRKPDVSHGEMV SGFGPIYNYKDTIVFKCQKGFVLRG SSVIHCDADSKWNPSPPACEPNSCI NLPDIPHASWETYPRPTKEDVYVVG TVLRYRCHPGYKPTTDEPTTVICQK NLRWTPYQGCEALCCPEPKLNNGEI TQHRKSRPANHCVYFYGDEISFSCH ETSRFSAICQGDGTWSPRTPSCGDI CNFPPKIAHGHYKQSSSYSFFKEEI IYECDKGYILVGQAKLSCSYSHWSA PAPQCKALCRKPELVNGRLSVDKDQ YVEPENVTIQCDSGYGVVGPQSITC SGNRTWYPEVPKCEWETPEGCEQVL TGKRLMQCLPNPEDVKMALEVYKLS LEIEQLELQRDSARQSTLDKELTRT RPLEQKLISEEDLAANDILDYKDDD DKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
