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Recombinant Human CAMK2A Protein, Myc/DDK-tagged, C13 and N15-labeled

Cat.No. : CAMK2A-6286H
Product Overview : CAMK2A MS Standard C13 and N15-labeled recombinant protein (NP_741960) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
  • Specification
  • Gene Information
  • Related Products
Description : The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Several transcript variants encoding distinct isoforms have been identified for this gene.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 54.1 kDa
AA Sequence : MATITCTRFTEEYQLFEELGKGAFS VVRRCVKVLAGQEYAAKIINTKKLS ARDHQKLEREARICRLLKHPNIVRL HDSISEEGHHYLIFDLVTGGELFED IVAREYYSEADASHCIQQILEAVLH CHQMGVVHRDLKPENLLLASKLKGA AVKLADFGLAIEVEGEQQAWFGFAG TPGYLSPEVLRKDPYGKPVDLWACG VILYILLVGYPPFWDEDQHRLYKQI KAGAYDFPSPEWDTVTPEAKDLINK MLTINPSKRITAAEALKHPWISHRS TVASCMHRQETVDCLKKFNARRKLK GAILTTMLATRNFSGGKSGGNKKSD GVKESSESTNTTIEDEDTKVRKQEI IKVTEQLIEAISNGDFESYTKMCDP GMTAFEPEALGNLVEGLDFHRFYFE NLWSRNSKPVHTTILNPHIHLMGDE SACIAYIRITQYLDAGGIPRTAQSE ETRVWHRRDGKWQIVHFHRSGAPSV LPHTRTRPLEQKLISEEDLAANDIL DYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Name : CAMK2A calcium/calmodulin-dependent protein kinase II alpha [ Homo sapiens (human) ]
Official Symbol : CAMK2A
Synonyms : CAMK2A; calcium/calmodulin-dependent protein kinase II alpha; calcium/calmodulin dependent protein kinase (CaM kinase) II alpha, CAMKA; calcium/calmodulin-dependent protein kinase type II subunit alpha; calcium/calmodulin dependent protein kinase II alpha B subunit; calcium/calmodulin dependent protein kinase type II alpha chain; CaM kinase II alpha subunit; CaM kinase II alpha chain; CaMK II alpha subunit; CaMKIINalpha; KIAA0968; CaMK-II alpha subunit; caMK-II subunit alpha; CaM-kinase II alpha chain; caM kinase II subunit alpha; calcium/calmodulin-dependent protein kinase II alpha-B subunit; calcium/calmodulin-dependent protein kinase type II alpha chain; calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha; CAMKA;
Gene ID : 815
mRNA Refseq : NM_171825
Protein Refseq : NP_741960
MIM : 114078
UniProt ID : Q9UQM7

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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