| Description : |
This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding different isoforms have been described. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
67.6 kDa |
| AA Sequence : |
MEGKWLLCMLLVLGTAIVEAHDGHD DDVIDIEDDLDDVIEEVEDSKPDTT APPSSPKVTYKAPVPTGEVYFADSF DRGTLSGWILSKAKKDDTDDEIAKY DGKWEVEEMKESKLPGDKGLVLMSR AKHHAISAKLNKPFLFDTKPLIVQY EVNFQNGIECGGAYVKLLSKTPELN LDQFHDKTPYTIMFGPDKCGEDYKL HFIFRHKNPKTGIYEEKHAKRPDAD LKTYFTDKKTHLYTLILNPDNSFEI LVDQSVVNSGNLLNDMTPPVNPSRE IEDPEDRKPEDWDERPKIPDPEAVK PDDWDEDAPAKIPDEEATKPEGWLD DEPEYVPDPDAEKPEDWDEDMDGEW EAPQIANPRCESAPGCGVWQRPVID NPNYKGKWKPPMIDNPSYQGIWKPR KIPNPDFFEDLEPFRMTPFSAIGLE LWSMTSDIFFDNFIICADRRIVDDW ANDGWGLKKAADGAAEPGVVGQMIE AAEERPWLWVVYILTVALPVFLVIL FCCSGKKQTSGMEYKKTDAPQPDVK EEEEEKEEEKDKGDEEEEGEEKLEE KQKSDAEEDGGTVSQEEEDRKPKAE EDEILNRSPRNRKPRRETRTRPLEQ KLISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
