Recombinant Human CASP7 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: CASP7-6396H
• Product Overview: CASP7 MS Standard C13 and N15-labeled recombinant protein (NP_001218) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 34.3 kDa
• AA Sequence: MADEQGCIEEQGVEDSANEDSVDAK PDRSSFVPSLFSKKKKNVTMRSIKT TRDRVPTYQYNMNFEKLGKCIIINN KNFDKVTGMGVRNGTDKDAEALFKC FRSLGFDVIVYNDCSCAKMQDLLKK ASEEDHTNAACFACILLSHGEENVI YGKDGVTPIKDLTAHFRGDRCKTLL EKPKLFFIQACRGTELDDGIQADSG PINDTDANPRYKIPVEADFLFAYST VPGYYSWRSPGRGSWFVQALCSILE EHGKDLEIMQILTRVNDRVARHFES QSDDPHFHEKKQIPCVVSMLTKELY FSQTRTRPLEQKLISEEDLAANDIL DYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: CASP7 caspase 7 [ Homo sapiens (human) ]
• Official Symbol: CASP7
• Synonyms: CASP7; caspase 7, apoptosis-related cysteine peptidase; caspase 7, apoptosis related cysteine protease; caspase-7; CMH 1; ICE LAP3; MCH3; CASP-7; Lice2 alpha/beta/gamma; caspase 7 isoform delta; apoptotic protease MCH-3; ICE-like apoptotic protease 3; caspase 7, apoptosis-related cysteine protease; CMH-1; ICE-LAP3
• Gene ID: 840
• mRNA Refseq: NM_001227
• Protein Refseq: NP_001218
• MIM: 601761
• UniProt ID: P55210