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Recombinant Human CBX5 Protein, Myc/DDK-tagged, C13 and N15-labeled

Cat.No. : CBX5-3435H
Product Overview : CBX5 MS Standard C13 and N15-labeled recombinant protein (NP_001120793) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
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  • Gene Information
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Description : This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 22.2 kDa
AA Sequence : MGKKTKRTADSSSSEDEEEYVVEKV LDRRVVKGQVEYLLKWKGFSEEHNT WEPEKNLDCPELISEFMKKYKKMKE GENNKPREKSESNKRKSNFSNSADD IKSKKKREQSNDIARGFERGLEPEK IIGATDSCGDLMFLMKWKDTDEADL VLAKEANVKCPQIVIAFYEERLTWH AYPEDAENKEKETAKSTRTRPLEQK LISEEDLAANDILDYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Name : CBX5 chromobox homolog 5 [ Homo sapiens (human) ]
Official Symbol : CBX5
Synonyms : CBX5; chromobox homolog 5; chromobox homolog 5 (Drosophila HP1 alpha), chromobox homolog 5 (HP1 alpha homolog, Drosophila); chromobox protein homolog 5; HP1; HP1 alpha homolog (Drosophila); HP1 ALPHA; HP1Hs alpha; HP1-ALPHA; antigen p25; HP1 alpha homolog; heterochromatin protein 1-alpha; heterochromatin protein 1 homolog alpha; chromobox homolog 5 (HP1 alpha homolog, Drosophila); HP1A;
Gene ID : 23468
mRNA Refseq : NM_001127321
Protein Refseq : NP_001120793
MIM : 604478
UniProt ID : P45973

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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