Active Recombinant Human CCL20
Cat.No. : | CCL20-296H |
Product Overview : | Recombinant human MIP-3α is a non-glycosylated protein, containing 70 amino acids and a molecular weight of 8.0 kDa. |
- Specification
- Gene Information
- Related Products
Description : | Macrophage Inflammatory Protein-3 alpha (MIP-3α), also called CCL20, is expressed in the liver, lungs, lymph nodes and peripheral blood lymphocytes. MIP-3α is strongly up regulated by inflammatory signals, and down regulated by the antiinflammatory cytokine IL-10. MIP-3α signals through the G protein-coupled receptor, CCR6, and acts as a chemoattractant to lymphocytes and dendritic cells. |
Source : | E.coli |
Species : | Human |
Appearance : | Sterile filtered white lyophilized (freeze-dried) powder. |
Form : | Recombinant human MIP-3α is lyophilized with no additives. |
Bio-activity : | The activity is determined by its ability to act as a chemoattractant to human T cells and is typically in the range of 7 - 70 ng/mL. |
Molecular Mass : | 8.0 kDa |
AA Sequence : | ASNFDCCLGY TDRILHPKFI VGFTRQLANE GCDINAIIFH TKKKLSVCAN PKQTWVKYIV RLLSKKVKNM |
Endotoxin : | Measured by kinetic LAL analysis and is typically ≤ 1 EU/μg protein. |
Purity : | ≥ 97% |
Stability : | Lyophilized product is very stable at -20°C. Reconstituted material should be aliquoted and frozen at -20°C. It is recommended that a carrier protein (0.1% HSA or BSA) is added for long term storage. |
Reconstitution : | Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at a concentration of 0.1 mg/mL, which can be further diluted into other aqueous solutions. |
Gene Name : | CCL20 chemokine (C-C motif) ligand 20 [ Homo sapiens (human) ] |
Official Symbol : | CCL20 |
Synonyms : | CCL20; CKb4; LARC; ST38; MIP3A; MIP-3a; SCYA20; MIP-3-alpha; C-C motif chemokine 20; chemokine (C-C motif) ligand 20; CC chemokine LARC; beta chemokine exodus-1; small-inducible cytokine A20; macrophage inflammatory protein 3 alpha; liver and activation-regulated chemokine; small inducible cytokine subfamily A (Cys-Cys), member 20 |
Gene ID : | 6364 |
mRNA Refseq : | NM_004591 |
Protein Refseq : | NP_004582 |
MIM : | 601960 |
UniProt ID : | P78556 |
Chromosome Location : | 2q36.3 |
Pathway : | Chemokine receptors bind chemokines; Chemokine signaling pathway; Class A/1 (Rhodopsin-like receptors) |
Function : | chemokine activity |
Products Types
◆ Recombinant Protein | ||
CCL20-512R | Recombinant Rhesus Macaque CCL20 Protein, His (Fc)-Avi-tagged | +Inquiry |
CCL20-18M | Recombinant Mouse CCL20 Protein | +Inquiry |
CCL20-793M | Recombinant Mouse CCL20 Protein (Ala28-Met97) | +Inquiry |
CCL20-0624H | Recombinant Human CCL20 Protein, GST-Tagged | +Inquiry |
CCL20-870R | Recombinant Rat CCL20 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
CCL20-447MCL | Recombinant Mouse CCL20 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (7)
Ask a questionCCL20 influences dendritic cell migration and differentiation, crucial for initiating immune responses.
CCL20 contributes to cancer progression by shaping the tumor microenvironment and aiding tumor cell invasion.
CCL20 plays a significant role in autoimmune diseases by attracting inflammatory cells to affected joints.
CCL20 is involved in wound healing and tissue repair, facilitating immune cell migration and tissue regeneration.
Changes in CCL20 expression impact skin health, potentially contributing to the development of skin disorders.
CCL20 recruits and activates immune cells to sites of inflammation, coordinating the immune response.
CCL20 impacts mucosal immunity, playing a critical role in immune defense in the gut and respiratory system.
Customer Reviews (3)
Write a reviewExpert protein engineering support, essential for our projects' progress.
Consistent western blot results, an indispensable tool in our lab.
Dependable protein quantification, ensures data precision in our work.
Ask a Question for All CCL20 Products
Required fields are marked with *
My Review for All CCL20 Products
Required fields are marked with *
Inquiry Basket