Recombinant Human CD27 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: CD27-6351H
• Product Overview: CD27 MS Standard C13 and N15-labeled recombinant protein (NP_001233) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 29.2 kDa
• AA Sequence: MARPHPWWLCVLGTLVGLSATPAPK SCPERHYWAQGKLCCQMCEPGTFLV KDCDQHRKAAQCDPCIPGVSFSPDH HTRPHCESCRHCNSGLLVRNCTITA NAECACRNGWQCRDKECTECDPLPN PSLTARSSQALSPHPQPTHLPYVSE MLEARTAGHMQTLADFRQLPARTLS THWPPQRSLCSSDFIRILVIFSGMF LVFTLAGALFLHQRRKYRSNKGESP VEPAEPCRYSCPREEEGSTIPIQED YRKPEPACSPTRTRPLEQKLISEED LAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: CD27 CD27 molecule [ Homo sapiens (human) ]
• Official Symbol: CD27
• Synonyms: CD27; CD27 molecule; TNFRSF7, tumor necrosis factor receptor superfamily, member 7; CD27 antigen; S152; Tp55; CD27L receptor; T cell activation antigen S152; T-cell activation antigen CD27; tumor necrosis factor receptor superfamily, member 7; T14; TNFRSF7; MGC20393
• Gene ID: 939
• mRNA Refseq: NM_001242
• Protein Refseq: NP_001233
• MIM: 186711
• UniProt ID: P26842