Recombinant Human CD36 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: CD36-2828H
• Product Overview: CD36 MS Standard C13 and N15-labeled recombinant protein (NP_001001548) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants have been found for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 53.1 kDa
• AA Sequence: MGCDRNCGLIAGAVIGAVLAVFGGI LMPVGDLLIQKTIKKQVVLEEGTIA FKNWVKTGTEVYRQFWIFDVQNPQE VMMNSSNIQVKQRGPYTYRVRFLAK ENVTQDAEDNTVSFLQPNGAIFEPS LSVGTEADNFTVLNLAVAAASHIYQ NQFVQMILNSLINKSKSSMFQVRTL RELLWGYRDPFLSLVPYPVTTTVGL FYPYNNTADGVYKVFNGKDNISKVA IIDTYKGKRNLSYWESHCDMINGTD AASFPPFVEKSQVLQFFSSDICRSI YAVFESDVNLKGIPVYRFVLPSKAF ASPVENPDNYCFCTEKIISKNCTSY GVLDISKCKEGRPVYISLPHFLYAS PDVSEPIDGLNPNEEEHRTYLDIEP ITGFTLQFAKRLQVNLLVKPSEKIQ VLKNLKRNYIVPILWLNETGTIGDE KANMFRSQVTGKINLLGLIEMILLS VGVVMFVAFMISYCACRSKTIKTRT RPLEQKLISEEDLAANDILDYKDDD DKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: CD36 CD36 molecule [ Homo sapiens (human) ]
• Official Symbol: CD36
• Synonyms: CD36; CD36 molecule (thrombospondin receptor); CD36 antigen (collagen type I receptor, thrombospondin receptor); platelet glycoprotein 4; FAT; GP3B; GP4; GPIV; SCARB3; GPIIIB; PAS IV; PAS-4 protein; glycoprotein IIIb; cluster determinant 36; fatty acid translocase; platelet glycoprotein IV; scavenger receptor class B, member 3; leukocyte differentiation antigen CD36; CHDS7; PASIV; BDPLT10
• Gene ID: 948
• mRNA Refseq: NM_001001548
• Protein Refseq: NP_001001548
• MIM: 173510
• UniProt ID: P16671