Recombinant Human CD59 Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | CD59-5367H |
Product Overview : | CD59 MS Standard C13 and N15-labeled recombinant protein (NP_000602) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 14.2 kDa |
AA Sequence : | MGIQGGSVLFGLLLVLAVFCHSGHS LQCYNCPNPTADCKTAVNCSSDFDA CLITKAGLQVYNKCWKFEHCNFNDV TTRLRENELTYYCCKKDLCNFNEQL ENGGTSLSEKTVLLLVTPFLAAAWS LHPTRTRPLEQKLISEEDLAANDIL DYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | CD59 CD59 molecule (CD59 blood group) [ Homo sapiens (human) ] |
Official Symbol : | CD59 |
Synonyms : | CD59; CD59 molecule, complement regulatory protein; CD59 antigen p18 20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344), CD59 antigen, complement regulatory protein, MIC11, MIN1, MIN2, MIN3, MSK21; CD59 glycoprotein; 16.3A5; EJ16; EJ30; EL32; G344; p18 20; protectin; 1F5 antigen; MEM43 antigen; Ly-6-like protein; T cell-activating protein; human leukocyte antigen MIC11; lymphocytic antigen CD59/MEM43; 20 kDa homologous restriction factor; membrane inhibitor of reactive lysis; membrane attack complex inhibition factor; membrane attack complex (MAC) inhibition factor; surface anitgen recognized by monoclonal 16.3A5; CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344); 1F5; MIN1; MIN2; MIN3; MIRL; HRF20; MACIF; MEM43; MIC11; MSK21; HRF-20; MAC-IP; p18-20; MGC2354; FLJ38134; FLJ92039; |
Gene ID : | 966 |
mRNA Refseq : | NM_000611 |
Protein Refseq : | NP_000602 |
MIM : | 107271 |
UniProt ID : | P13987 |
Products Types
◆ Recombinant Protein | ||
CD59-692H | Recombinant Human CD59 Protein, His and C-hFc-tagged | +Inquiry |
CD59-572R | Recombinant Rhesus Macaque CD59 Protein, His (Fc)-Avi-tagged | +Inquiry |
CD59-543H | Recombinant Human CD59 Protein, His (Fc)-Avi-tagged | +Inquiry |
CD59-140C | Recombinant Cynomolgus Monkey CD59 Protein, His (Fc)-Avi-tagged | +Inquiry |
CD59-918R | Recombinant Rat CD59 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
CD59-1968HCL | Recombinant Human CD59 cell lysate | +Inquiry |
CD59-1365RCL | Recombinant Rat CD59 cell lysate | +Inquiry |
CD59-1019CCL | Recombinant Cynomolgus CD59 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket