Recombinant Human CDC42EP4 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: CDC42EP4-2299H
• Product Overview: CDC42EP4 MS Standard C13 and N15-labeled recombinant protein (NP_036253) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The product of this gene is a member of the CDC42-binding protein family. Members of this family interact with Rho family GTPases and regulate the organization of the actin cytoskeleton. This protein has been shown to bind both CDC42 and TC10 GTPases in a GTP-dependent manner. When overexpressed in fibroblasts, this protein was able to induce pseudopodia formation, which suggested a role in inducing actin filament assembly and cell shape control.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 38 kDa
• AA Sequence: MPILKQLVSSSVHSKRRSRADLTAE MISAPLGDFRHTMHVGRAGDAFGDT SFLNSKAGEPDGESLDEQPSSSSSK RSLLSRKFRGSKRSQSVTRGEREQR DMLGSLRDSALFVKNAMSLPQLNEK EAAEKGTSKLPKSLSSSPVKKANDG EGGDEEAGTEEAVPRRNGAAGPHSP DPLLDEQAFGDLTDLPVVPKATYGL KHAESIMSFHIDLGPSMLGDVLSIM DKEEWDPEEGEGGYHGDEGAAGTIT QAPPYAVAAPPLARQEGKAGPDLPS LPSHALEDEGWAAAAPSPGSARSMG SHTTRDSSSLSSCTSGILEERSPAF RGPDRARAAVSRQPDKEFSFMDEEE EDEIRVTRTRPLEQKLISEEDLAAN DILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: CDC42EP4 CDC42 effector protein 4 [ Homo sapiens (human) ]
• Official Symbol: CDC42EP4
• Synonyms: CDC42EP4; CDC42 effector protein (Rho GTPase binding) 4; cdc42 effector protein 4; binder of Rho GTPases 4; BORG4; Cdc42 effector protein 4; CEP4; KAIA1777; MGC3740; MGC17125
• Gene ID: 23580
• mRNA Refseq: NM_012121
• Protein Refseq: NP_036253
• MIM: 605468
• UniProt ID: Q9H3Q1